ID   L0EAU6_THECK            Unreviewed;       617 AA.
AC   L0EAU6;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=HAMP domain-containing protein,histidine kinase {ECO:0000313|EMBL:AGA56280.1};
GN   OrderedLocusNames=Theco_0022 {ECO:0000313|EMBL:AGA56280.1};
OS   Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Thermobacillus.
OX   NCBI_TaxID=717605 {ECO:0000313|EMBL:AGA56280.1, ECO:0000313|Proteomes:UP000010795};
RN   [1] {ECO:0000313|Proteomes:UP000010795}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18247 / JCM 13945 / KWC4
RC   {ECO:0000313|Proteomes:UP000010795};
RA   Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Peters L., Ovchinnikova G., Teshima H., Detter J.C., Han C., Tapia R.,
RA   Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Anderson I.,
RA   Woyke T.;
RT   "Complete sequence of chromosome of Thermobacillus composti KWC4.";
RL   Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP003255; AGA56280.1; -; Genomic_DNA.
DR   RefSeq; WP_015253048.1; NC_019897.1.
DR   AlphaFoldDB; L0EAU6; -.
DR   STRING; 717605.Theco_0022; -.
DR   KEGG; tco:Theco_0022; -.
DR   eggNOG; COG2972; Bacteria.
DR   HOGENOM; CLU_020473_6_1_9; -.
DR   OrthoDB; 9809348at2; -.
DR   Proteomes; UP000010795; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR   PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR   PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF06580; His_kinase; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AGA56280.1};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010795};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        316..338
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          335..387
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   COILED          368..407
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   617 AA;  70119 MW;  0BBCA352FB50E4E1 CRC64;
     MPDWMNRIRR LAGKPSERLV RKLILLFAGL AMLIVLLLTF ISYKMIERQS VESFVAGSKS
     NLMLVNKNIV RYFAEIDQMS TPGLQYDALI QAAECGTCDY TAQIFLENYV RSMFHSRNDI
     ESLFFYLPSH NQYYAISKGE PGRTVRIVSD EEGRIARQKW MAMVLDRDTN RLIQTLLLDE
     SVGYARTKDS YIAYHRVIRT LLEREPMAVL TILFSPGGRD EILRDVALAQ GEQLLLADAE
     GRPFYWSDPA FFEQAPLTEW LADIRADEDG VLDRVLGGER YMVIGDMDQT TGWTLVKWTP
     YRLIYASAQK TRNVSILLGS VFVLFALLAV SLMSNAITRP LKALTRKMEA FSRGNFNVMV
     EVRGQDEIAL LSRQFNRMVR QIEELINERY RMQLAEKNAV LKALEAELNP HFMYNALQTI
     STNALKKGVP EVADMVDALA GTLRYSISRR DRVLLREEIQ HIERYLAIQK ARFGGRLQVR
     FELDDRLPDV EIPKLSVQTL VENAVKHGVE KTSVPVLIRI RAWPDKLGTV IAVHDSGPGM
     DGEQLELLRE RLARDWDDRE QQGNASIGLS NLAARLKLLY GDAARLMIDS DELGTEVRIL
     IPRGGNDGND SGADHRG
//