ID L0EF27_THECK Unreviewed; 590 AA.
AC L0EF27;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN OrderedLocusNames=Theco_1623 {ECO:0000313|EMBL:AGA57760.1};
OS Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4).
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Thermobacillus.
OX NCBI_TaxID=717605 {ECO:0000313|EMBL:AGA57760.1, ECO:0000313|Proteomes:UP000010795};
RN [1] {ECO:0000313|Proteomes:UP000010795}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18247 / JCM 13945 / KWC4
RC {ECO:0000313|Proteomes:UP000010795};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Anderson I.,
RA Woyke T.;
RT "Complete sequence of chromosome of Thermobacillus composti KWC4.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC {ECO:0000256|ARBA:ARBA00005336}.
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DR EMBL; CP003255; AGA57760.1; -; Genomic_DNA.
DR AlphaFoldDB; L0EF27; -.
DR STRING; 717605.Theco_1623; -.
DR KEGG; tco:Theco_1623; -.
DR eggNOG; COG1472; Bacteria.
DR HOGENOM; CLU_008392_5_3_9; -.
DR Proteomes; UP000010795; Chromosome.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR InterPro; IPR001764; Glyco_hydro_3_N.
DR InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR30480:SF13; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR30480; BETA-HEXOSAMINIDASE-RELATED; 1.
DR Pfam; PF00933; Glyco_hydro_3; 1.
DR PRINTS; PR00133; GLHYDRLASE3.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AGA57760.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010795}.
FT DOMAIN 21..342
FT /note="Glycoside hydrolase family 3 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00933"
SQ SEQUENCE 590 AA; 63184 MW; 309202EED1403CF8 CRC64;
MSKAGAWRGT GEGVNLAGWS LRDKIGQMVM AGFDGKAPTD EIRALIRERK LGGVIYFRRN
AGSVAEVARL SAALRELAAE ATKVPLWIAV DQEGGMVARL DQGVTVMPGH MALGATRSAK
WARETAYASG AQLMRLGVNL NFAPCLDVNN NPANPVIGVR SFGERPELAA ELGIAAIRGY
REAGVVACAK HFPGHGDTVA DSHRELPTVP HDRKRLEEVE LLPFRLAAAA GADAIMTAHV
RFPALEPDGL PATLSPRILR GLLRDEWGYD GVVFTDCLEM KAIAGTVGVA RGAVMAVKAG
ADVVLVSHTP ALQKAALDAL YEAVEAGEIA EARIDESVRR IAGLKARQSA AVPVGPVPAA
RSDAGTGPDD FDFGGEAAAL AREVCRRSVT LVRNERGALP LRRDVPTFVV WPEVRQGTEV
DEALARELTL GRALAPYLSR VKEFRIGTVP GEDEVRETLA EIDRALEDIR ERAAVRGEPG
SDRTLLQVVV GTYNAAFAAG QTELVNHLLA CEGVRVTAAA LRNPYDFLAF PEVHAYAACY
ENTPCMMEAL AEVLAGETEA RGRLPVTLSE RYPFGHGISG FRKERDGEET
//
