ID L0EH51_THECK Unreviewed; 455 AA.
AC L0EH51;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Membrane-bound serine protease (ClpP class) {ECO:0000313|EMBL:AGA58485.1};
GN OrderedLocusNames=Theco_2375 {ECO:0000313|EMBL:AGA58485.1};
OS Thermobacillus composti (strain DSM 18247 / JCM 13945 / KWC4).
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Thermobacillus.
OX NCBI_TaxID=717605 {ECO:0000313|EMBL:AGA58485.1, ECO:0000313|Proteomes:UP000010795};
RN [1] {ECO:0000313|Proteomes:UP000010795}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18247 / JCM 13945 / KWC4
RC {ECO:0000313|Proteomes:UP000010795};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Ovchinnikova G., Teshima H., Detter J.C., Han C., Tapia R.,
RA Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Anderson I.,
RA Woyke T.;
RT "Complete sequence of chromosome of Thermobacillus composti KWC4.";
RL Submitted (JAN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP003255; AGA58485.1; -; Genomic_DNA.
DR RefSeq; WP_015255229.1; NC_019897.1.
DR AlphaFoldDB; L0EH51; -.
DR STRING; 717605.Theco_2375; -.
DR KEGG; tco:Theco_2375; -.
DR eggNOG; COG1030; Bacteria.
DR HOGENOM; CLU_024619_2_0_9; -.
DR OrthoDB; 9806253at2; -.
DR Proteomes; UP000010795; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07021; Clp_protease_NfeD_like; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR002810; NfeD-like_C.
DR InterPro; IPR002825; Pept_S49_ser-pept_pro.
DR PANTHER; PTHR33507; INNER MEMBRANE PROTEIN YBBJ; 1.
DR PANTHER; PTHR33507:SF3; INNER MEMBRANE PROTEIN YBBJ; 1.
DR Pfam; PF01957; NfeD; 1.
DR Pfam; PF01972; SDH_sah; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR SUPFAM; SSF141322; NfeD domain-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:AGA58485.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000313|EMBL:AGA58485.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010795};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..455
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003941591"
FT TRANSMEM 247..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 357..450
FT /note="NfeD-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01957"
SQ SEQUENCE 455 AA; 47191 MW; FDA75D2DBE186349 CRC64;
MRPLNLRSRL RAAAAALMLI AALLAAIVPA VQAADSGAGG AGPAVYVIPV RQTIESGLEA
FLKRAFREAE EARAERIVLV INTNGGRLEN AQNIGDLVGA SPVPVTAFVE SKAFSAGAYI
ALNADQIVMR PGSSIGAAAM VDAAGNLVDN PKQISAWTAE MRDAAEASGR DPNIAAAMAD
PNYRGEIPGI GRDPGGILTL TAEEALRVGY ADHLADSVED VIAWLGLEQR AVVHVDPSLA
ERAARVLTQP GVMLLLLIIG IAGIVIEMLV PGFGVPGIVG LLALVLYFFG QYVAGFAGME
SVALFVAGII LLVLELFVPS YGILGILGGA AIIGGIATAA YDAGDAVTTL LYAFGAAAVL
AAIAGYIFRK RGVWNKFILR ESLTSEEGYL STEARTDLTG KSGTALTPLR PAGVVLIDGE
RIDAVSEGGF VEPGARVRVV RAEGLRVVVK ESKDE
//
