ID L0IWM4_9MYCO Unreviewed; 322 AA.
AC L0IWM4;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Theronine dehydrogenase-like Zn-dependent dehydrogenase {ECO:0000313|EMBL:AGB22727.1};
GN ORFNames=Mycsm_02387 {ECO:0000313|EMBL:AGB22727.1};
OS Mycobacterium sp. JS623.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=212767 {ECO:0000313|EMBL:AGB22727.1, ECO:0000313|Proteomes:UP000010844};
RN [1] {ECO:0000313|Proteomes:UP000010844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JS623 {ECO:0000313|Proteomes:UP000010844};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Mattes T., Holmes A., Rutledge P.,
RA Paulsen I., Coleman N., Woyke T.;
RT "Complete sequence of chromosome of Mycobacterium smegmatis JS623.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR EMBL; CP003078; AGB22727.1; -; Genomic_DNA.
DR RefSeq; WP_015306307.1; NC_019966.1.
DR AlphaFoldDB; L0IWM4; -.
DR STRING; 212767.Mycsm_02387; -.
DR KEGG; msa:Mycsm_02387; -.
DR PATRIC; fig|710686.3.peg.2404; -.
DR HOGENOM; CLU_026673_11_0_11; -.
DR OrthoDB; 9797931at2; -.
DR Proteomes; UP000010844; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43401; L-THREONINE 3-DEHYDROGENASE; 1.
DR PANTHER; PTHR43401:SF2; L-THREONINE 3-DEHYDROGENASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 28..93
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 156..264
FT /note="Alcohol dehydrogenase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00107"
SQ SEQUENCE 322 AA; 34642 MW; 706B89499DE9195A CRC64;
MWAYRLVAPY TFERVDIPEK TPGSLGDRQV LLRFLAAGIC GSDLPGFRGS KGRLPGDTGV
SAAEMDGFPI HEVVGEVIAS RHRSHGVGDR VVGWASGFDG LMEHVVADGE GLAPFDPALT
PQHAVALQPL ACVLYVLEQI PNIKGSHVAV IGQGSIGLLF SYAAKAFGAR HVTGVDPIDR
DGIGKEFGVD TIVRAPSDRW VSHLDANDRP DIVIEAVGHQ VATLNHAIEA AAFGGTVFYF
GVPDDDSYPI SMRTMLRNNL TLKSGVTLDR RRVLCSASEF ARKHPELLRA YVSHTFGVDE
VQAAFELACR PTPVRIKIAI VA
//
