ID L0IZE9_9MYCO Unreviewed; 923 AA.
AC L0IZE9;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE SubName: Full=Beta-galactosidase/beta-glucuronidase {ECO:0000313|EMBL:AGB23722.1};
DE Flags: Precursor;
GN ORFNames=Mycsm_03422 {ECO:0000313|EMBL:AGB23722.1};
OS Mycobacterium sp. JS623.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=212767 {ECO:0000313|EMBL:AGB23722.1, ECO:0000313|Proteomes:UP000010844};
RN [1] {ECO:0000313|Proteomes:UP000010844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JS623 {ECO:0000313|Proteomes:UP000010844};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Mattes T., Holmes A., Rutledge P.,
RA Paulsen I., Coleman N., Woyke T.;
RT "Complete sequence of chromosome of Mycobacterium smegmatis JS623.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
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DR EMBL; CP003078; AGB23722.1; -; Genomic_DNA.
DR AlphaFoldDB; L0IZE9; -.
DR STRING; 212767.Mycsm_03422; -.
DR KEGG; msa:Mycsm_03422; -.
DR PATRIC; fig|710686.3.peg.3450; -.
DR HOGENOM; CLU_005015_2_4_11; -.
DR OrthoDB; 9758603at2; -.
DR Proteomes; UP000010844; Chromosome.
DR GO; GO:0052761; F:exo-1,4-beta-D-glucosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR043534; EBDG/EBM.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR041351; Ig_GlcNase.
DR InterPro; IPR041447; Mannosidase_ig.
DR PANTHER; PTHR43536; MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE; 1.
DR PANTHER; PTHR43536:SF1; MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF18368; Ig_GlcNase; 1.
DR Pfam; PF17786; Mannosidase_ig; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 3.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 84..197
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 260..362
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 714..794
FT /note="Mannosidase Ig/CBM-like"
FT /evidence="ECO:0000259|Pfam:PF17786"
FT DOMAIN 814..915
FT /note="Exo-beta-D-glucosaminidase Ig-fold"
FT /evidence="ECO:0000259|Pfam:PF18368"
SQ SEQUENCE 923 AA; 103141 MW; 7374C463131A6AA3 CRC64;
MSVERRRHIV LRILLSVALL LLLCAADFPD FAKSGPPPGQ IELAQGWSLI SASNVSADGA
ALSTPGYKAA GWHTIPRMPA TVLQTLQDDG TYPNLYYGTN LGAVPQDLYK QDWWYRTTFT
APAGHTAYQL EFPGINYRAE IWLNGHLIAG NTQIVGMHTA HELDVSRWVN QGEANALAVK
ITPERALQDV NGVELADSWY DWINWNYLGY QGPGKNPNNG NSFVPDRNAG IWKPVYLKTS
GAVALGPATV NSELPLPRTN SAKLTIYSSL HNASAQQVRG VLRATITRPG KPDLQVEQPV
TLAAGEQREI SFTPDKFAQL AVDNPDLWWP YTMGRPNLYD LHLEFRQFDR QIDAEHLRFG
IRSVQQFRDQ DEQFPELGKG GNFYLKVNGK DFLVRGAAYT PDLLYANDPS RDAAILGYVK
DLGLNMIRLE GKFPGDHITE MADEMGIPLM YGWMCCNQWE KWNQWGDEDI RVARDSLRSQ
IEGLRSHPSV FMWANGSDGR APDDVLAEYH SILSDLHWQN ATVDTVSTLA VHDLGERGWD
GIQMAGPYSW RPPSYWFSGR YPATRGSTAE QGDNESIPPF ASLKKFIPPD KLWPINDAWF
FHAGSDPRNA ELTSIRRAVD RRYGPSDDAE EFTRKAQLAH YESTRAQFEA FAAGGWDNHK
MTIYWMLNNH WPSFFGHIFD YYLRPGGAYY GAKKGLRPLS VVFDSYATGN HDHANVTVVN
QTPSEKTGLT VRVRTYDLQG KVRDDRTAGN VNVPAGAATQ ALTLPRLVRD SSVYFVRAQL
LDSTGKILSE NTYWQSQQLD DVGDPGNDSA FELSQTSWAN MTGLNSMPQV PLDVTASKSA
DPGDNRVTIR LHNPSQRVAF FERAELVPTR EGDEILPVEY SDNYVTVFPG ETVELSGQAW
TGVTPNWVRV TGYNTPAQLV AIK
//
