ID L0IZV0_9MYCO Unreviewed; 362 AA.
AC L0IZV0;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Geranylgeranyl pyrophosphate synthase {ECO:0000313|EMBL:AGB24138.1};
GN ORFNames=Mycsm_03874 {ECO:0000313|EMBL:AGB24138.1};
OS Mycobacterium sp. JS623.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=212767 {ECO:0000313|EMBL:AGB24138.1, ECO:0000313|Proteomes:UP000010844};
RN [1] {ECO:0000313|Proteomes:UP000010844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JS623 {ECO:0000313|Proteomes:UP000010844};
RG US DOE Joint Genome Institute;
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Mattes T., Holmes A., Rutledge P.,
RA Paulsen I., Coleman N., Woyke T.;
RT "Complete sequence of chromosome of Mycobacterium smegmatis JS623.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Isoprenoid biosynthesis. {ECO:0000256|ARBA:ARBA00005128}.
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CP003078; AGB24138.1; -; Genomic_DNA.
DR RefSeq; WP_015307714.1; NC_019966.1.
DR AlphaFoldDB; L0IZV0; -.
DR STRING; 212767.Mycsm_03874; -.
DR KEGG; msa:Mycsm_03874; -.
DR PATRIC; fig|710686.3.peg.3904; -.
DR HOGENOM; CLU_014015_2_1_11; -.
DR OrthoDB; 4497239at2; -.
DR Proteomes; UP000010844; Chromosome.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001:SF88; (2E,6E)-FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022516};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 362 AA; 38646 MW; B9613F49362AF14E CRC64;
MDAAAPSAVE LAGAVTDQLR DYLRDRRSDA AYIGPDYAEL TAALEEFVLR GGKRLRPAFA
YWGWRAVADD DTNPADPSML RLFSALELLH ACALVHDDVI DASATRRGLP TVHRLFSEKH
RSSQWHGSCE QFGISAAILL GDLALVWADD IVATADLAPD AQARVRRVWS AIRTEVLGGQ
YLDIVAESSG AESVASAMTV NVYKTASYTI SRPLQFGAAA AADRPDVLAA FHELGTSLGV
AFQLRDDVLG VFGDPAVTGK PSGDDLRSGK RTVLLAEAVE RADKVDPVAA KLLRTSIGTE
LTDAQVRELC LVIESVGALA AVEGRIDSLT RRSLEILTAA QIDARAKVGL AELARLAANR
SA
//
