ID L0JDP9_PREDD Unreviewed; 678 AA.
AC L0JDP9;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Alpha-amylase {ECO:0000256|RuleBase:RU361134};
DE EC=3.2.1.1 {ECO:0000256|RuleBase:RU361134};
GN OrderedLocusNames=Prede_1123 {ECO:0000313|EMBL:AGB28451.1};
OS Prevotella dentalis (strain ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043
OS / ES 2772) (Mitsuokella dentalis).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=908937 {ECO:0000313|EMBL:AGB28451.1, ECO:0000313|Proteomes:UP000010862};
RN [1] {ECO:0000313|Proteomes:UP000010862}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043 / ES 2772
RC {ECO:0000313|Proteomes:UP000010862};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Chertkov O.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome 1 of Prevotella dentalis DSM 3688.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in
CC polysaccharides containing three or more (1->4)-alpha-linked D-
CC glucose units.; EC=3.2.1.1; Evidence={ECO:0000256|RuleBase:RU361134};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC {ECO:0000256|ARBA:ARBA00008061, ECO:0000256|RuleBase:RU003615}.
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DR EMBL; CP003368; AGB28451.1; -; Genomic_DNA.
DR AlphaFoldDB; L0JDP9; -.
DR KEGG; pdt:Prede_1123; -.
DR PATRIC; fig|908937.9.peg.1170; -.
DR HOGENOM; CLU_017998_0_0_10; -.
DR OrthoDB; 9806009at2; -.
DR Proteomes; UP000010862; Chromosome 1.
DR GO; GO:0004556; F:alpha-amylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0043169; F:cation binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd11314; AmyAc_arch_bac_plant_AmyA; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR006046; Alpha_amylase.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR43447; ALPHA-AMYLASE; 1.
DR PANTHER; PTHR43447:SF49; ALPHA-AMYLASE; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR PRINTS; PR00110; ALPHAAMYLASE.
DR SMART; SM00642; Aamy; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU361134};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361134};
KW Reference proteome {ECO:0000313|Proteomes:UP000010862};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..678
FT /note="Alpha-amylase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003944381"
FT DOMAIN 29..361
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
SQ SEQUENCE 678 AA; 73999 MW; F72086D05C1562C1 CRC64;
MKRFHTFMMA ALTLPMTMAA QGWPADYGGV MLQGFYWDGF KDAKWTRLER QAADFSGYFD
LVWVPQSGKT QGGLSMGYDP YYYFNQNSSF GSESELRSMM KTFKDKGIGT IADVVVNHRS
TSGWFTFPAE TYQGVTYQMT PQDITANDDG GATARQAILE GVTLSSNIDE GEDFGGFRDL
DHKSTNVQTI VKAYAKYLID DLGYTGFRYD VAKGFAPSHL ADYNNYAGPK FAVGEVWDGD
AKIKSVINGS GKTTAAFDFQ FRYTVRNAVG SGDWSRLGQQ NDDNWPLVSS SNDNGAYRQY
AVTFVENHDT EQRSATNQQD PIRRDTLAAN AYMLAMPGTP CVFYKHYLAY PNEIKAMIDV
RKAAGIANTS SYNNYRSSKA YYANTVNGSR GTLLVCVGSG FTDPAASRYV KVLSGRHYAL
YLSPSTEVAF ADKPSGTYAE AFSTRLTAVS ANGGARLVYT TDSSDPSASN GTTVDSGTSV
AIGQDCTLKV GLLVGGQVTH TVTRQYTIKA GEVEDSVVYE TPPAGYTYHA YFIAPASWGS
EADVYAWAWV ENGANYTPDN NASWPGDNEH VYRIAKAGDG GYVWQWCYYG TETTPPAMII
FNNGSSGVGT NQTKDMTFTD GGWYNIGTTE ANPTLGIQRG MTVGTGDDGA WHTLSGIRLG
GRPTQKGVYV HQGKKVVK
//
