ID L0JIJ5_NATP1 Unreviewed; 647 AA.
AC L0JIJ5;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=DNA (cytosine-5-)-methyltransferase {ECO:0000256|ARBA:ARBA00011975};
DE EC=2.1.1.37 {ECO:0000256|ARBA:ARBA00011975};
GN OrderedLocusNames=Natpe_1239 {ECO:0000313|EMBL:AGB31144.1};
OS Natrinema pellirubrum (strain DSM 15624 / CIP 106293 / JCM 10476 / NCIMB
OS 786 / 157).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natrinema.
OX NCBI_TaxID=797303 {ECO:0000313|EMBL:AGB31144.1, ECO:0000313|Proteomes:UP000010843};
RN [1] {ECO:0000313|Proteomes:UP000010843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15624 / JCM 10476 / NCIMB 786
RC {ECO:0000313|Proteomes:UP000010843};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Sproer C., Anderson I., Woyke T.;
RT "Complete sequence of chromosome of Natrinema pellirubrum DSM 15624.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. C5-methyltransferase family.
CC {ECO:0000256|RuleBase:RU000416}.
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DR EMBL; CP003372; AGB31144.1; -; Genomic_DNA.
DR AlphaFoldDB; L0JIJ5; -.
DR STRING; 797303.Natpe_1239; -.
DR REBASE; 58792; M.Npe15624ORF1239P.
DR KEGG; npe:Natpe_1239; -.
DR eggNOG; arCOG04157; Archaea.
DR HOGENOM; CLU_412076_0_0_2; -.
DR OrthoDB; 5033at2157; -.
DR Proteomes; UP000010843; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:0034641; P:cellular nitrogen compound metabolic process; IEA:UniProt.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR018117; C5_DNA_meth_AS.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00675; dcm; 1.
DR PANTHER; PTHR10629; CYTOSINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10629:SF52; DNA (CYTOSINE-5)-METHYLTRANSFERASE 1; 1.
DR Pfam; PF00145; DNA_methylase; 1.
DR PRINTS; PR00105; C5METTRFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00094; C5_MTASE_1; 1.
DR PROSITE; PS51679; SAM_MT_C5; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 394..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 647 AA; 72854 MW; CEE6515C92D2197D CRC64;
MSDRIRVASL FTGAGGLDIG FSTLSEFDVR FHTDIDDIAI DTLRTNAERG SYIDDDAIIE
RTDITEYDGG DLEPDEVDLV IGGPPCQPFS AAARRSGGFA GADSEDGQLF RAYVKLLERW
QPRAFLFENV YGITSDEEDW QMIVDAFENE AGDPGYRLTA RTLDAADYGV PQHRARTFIV
GVRKDVDEEF RFPRPTHGPD SPADRDLVTA GEALADLETA GAAEDPTYEI TSKHAHLLAD
IPPGLNYSFY TEKLGHPEPV FGWRSRFSDY LYKADPERPV RTLKAQPGAA SGPFHWENRK
FTEAELKRLQ AFPDDYVLEG SYGQVVKQIG NSVPPRIAEV LAKAIAEELF GAEGDDDVVP
MPDGYDLNFR SRKRTSTEEY RRKARERLEE LGLWDPRNER SGQQRGLEEY GDSSDDETEP
EATRRRATLH YRDHFERERL SYGTDVEPDG AGRTFDTESD VEGGTLRVDI ERQHGGEGTI
EIVLEPDDGI WNGIGSLEVT AIGVDLDDIF YVWDIAATDV IERTRYEKFI DVVGHYSTTR
LDYSSSLELT GVDAGLVPRT LQFFSQASNC NTEFTLDELG RQLDATHEEL VDALRQLRGW
RYELRTPATH ETMPEGKVLC TYPFPDMNER SHFDSEIELD ALETRTN
//
