ID L0JUC5_9EURY Unreviewed; 346 AA.
AC L0JUC5;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Formyltetrahydrofolate hydrolase {ECO:0000313|EMBL:AGB36341.1};
DE EC=3.5.1.10 {ECO:0000313|EMBL:AGB36341.1};
GN ORFNames=Natoc_0478 {ECO:0000313|EMBL:AGB36341.1};
OS Natronococcus occultus SP4.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronococcus.
OX NCBI_TaxID=694430 {ECO:0000313|EMBL:AGB36341.1, ECO:0000313|Proteomes:UP000010878};
RN [1] {ECO:0000313|EMBL:AGB36341.1, ECO:0000313|Proteomes:UP000010878}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP4 {ECO:0000313|EMBL:AGB36341.1,
RC ECO:0000313|Proteomes:UP000010878};
RG DOE Joint Genome Institute;
RA Eisen J., Huntemann M., Wei C.-L., Han J., Detter J.C., Han C., Tapia R.,
RA Chen A., Kyrpides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L.,
RA Nordberg H.P., Cantor M.N., Hua S.X., Woyke T., Eisen J., Klenk H.-P.,
RA Klenk H.-P.;
RT "FINISHED of Natronococcus occultus SP4, DSM 3396.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003929; AGB36341.1; -; Genomic_DNA.
DR RefSeq; WP_015319797.1; NC_019974.1.
DR AlphaFoldDB; L0JUC5; -.
DR STRING; 694430.Natoc_0478; -.
DR GeneID; 14405506; -.
DR KEGG; nou:Natoc_0478; -.
DR eggNOG; arCOG02826; Archaea.
DR HOGENOM; CLU_038395_3_0_2; -.
DR OrthoDB; 27277at2157; -.
DR Proteomes; UP000010878; Chromosome.
DR GO; GO:0008864; F:formyltetrahydrofolate deformylase activity; IEA:UniProtKB-EC.
DR GO; GO:0006189; P:'de novo' IMP biosynthetic process; IEA:InterPro.
DR GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.50.170; Formyl transferase, N-terminal domain; 1.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR002376; Formyl_transf_N.
DR InterPro; IPR036477; Formyl_transf_N_sf.
DR InterPro; IPR004810; PurU.
DR PANTHER; PTHR42706; FORMYLTETRAHYDROFOLATE DEFORMYLASE; 1.
DR PANTHER; PTHR42706:SF1; FORMYLTETRAHYDROFOLATE DEFORMYLASE 1, MITOCHONDRIAL; 1.
DR Pfam; PF13740; ACT_6; 1.
DR Pfam; PF00551; Formyl_trans_N; 1.
DR PRINTS; PR01575; FFH4HYDRLASE.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF53328; Formyltransferase; 1.
DR PROSITE; PS51671; ACT; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:AGB36341.1};
KW One-carbon metabolism {ECO:0000256|ARBA:ARBA00022563};
KW Reference proteome {ECO:0000313|Proteomes:UP000010878}.
FT DOMAIN 7..83
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
FT REGION 277..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..304
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 321..339
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 346 AA; 38217 MW; BC64058B4DEC4092 CRC64;
MTTDLTEITV IGDDDTGLVA RVTSLLFERG ANIEDIDQAV RDDVFRMNLA VDTAEMVCTE
ATLREDLHEL GEDLGLDVQV RFPADRETQR IAVLGTSESH CLEALFEAWA NDELGADIGV
VIGNHDDLEP LAQRYDVPFH DIGDENGQQN EARLLELLAE YDADLIVLAR YMRILSPNVV
FRYEDRIINV HPSLLPAFPG AEAYRQALEE GVRVAGVTAH YVTTDLDQGP IITQRAFNVP
DDADLAEIKR RGQPLEADAL LEAVRLHLNG DVSVHRGRTS VRENERDYQL GLPDEMDELT
PDRPVDGIAD AVTDADPITD GDADAAPEEN DEDDADRETE PEPPAS
//
