ID L0K250_9EURY Unreviewed; 674 AA.
AC L0K250;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=Natoc_3348 {ECO:0000313|EMBL:AGB39081.1};
OS Natronococcus occultus SP4.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Natrialbales;
OC Natrialbaceae; Natronococcus.
OX NCBI_TaxID=694430 {ECO:0000313|EMBL:AGB39081.1, ECO:0000313|Proteomes:UP000010878};
RN [1] {ECO:0000313|EMBL:AGB39081.1, ECO:0000313|Proteomes:UP000010878}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP4 {ECO:0000313|EMBL:AGB39081.1,
RC ECO:0000313|Proteomes:UP000010878};
RG DOE Joint Genome Institute;
RA Eisen J., Huntemann M., Wei C.-L., Han J., Detter J.C., Han C., Tapia R.,
RA Chen A., Kyrpides N., Mavromatis K., Markowitz V., Szeto E., Ivanova N.,
RA Mikhailova N., Ovchinnikova G., Pagani I., Pati A., Goodwin L.,
RA Nordberg H.P., Cantor M.N., Hua S.X., Woyke T., Eisen J., Klenk H.-P.,
RA Klenk H.-P.;
RT "FINISHED of Natronococcus occultus SP4, DSM 3396.";
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP003929; AGB39081.1; -; Genomic_DNA.
DR RefSeq; WP_015322518.1; NC_019974.1.
DR AlphaFoldDB; L0K250; -.
DR STRING; 694430.Natoc_3348; -.
DR GeneID; 14401788; -.
DR KEGG; nou:Natoc_3348; -.
DR eggNOG; arCOG02360; Archaea.
DR eggNOG; arCOG06712; Archaea.
DR eggNOG; arCOG07605; Archaea.
DR HOGENOM; CLU_000445_114_71_2; -.
DR OrthoDB; 8127at2157; -.
DR Proteomes; UP000010878; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16921; HATPase_FilI-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000010878}.
FT DOMAIN 25..69
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 142..212
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 214..269
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 460..673
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 674 AA; 73871 MW; 423CEBD08FA354B9 CRC64;
MDAGSPDEPA DDAAPTRSAG SRLSLLETAS VPSVQLTSAG RIGDATAAFA SLTGYERSKL
LGRRFAELLA GEVPALDVLE AGNRRTPLST TCSLRTGAET VVDADLHLDP PDDNDPERRV
TAIVDPKPSL ARSSATQPEL TYGRTFEALA DAVPDGIIVL DSDSEIRYAN PAVERILGHD
PAELVGGSKV EIIPPRLRQT HLDALQRYLE TGERNLNWTY VELPGQHSDG YEIPLGISLN
DFVHDGDRYF VGLFRDISPR KEAEEMLTTK VAQLESVAYL SRYALENADD DELFRKASEL
VTAAFDAEYC AVLETETTDS GDERTAFRTR AAVGCEDAFL ESEPVSTAES LAAAACADGE
PVVVEDVAAD DRFDASSLLP DGEYHSGLAV AVGPAADAWG VLAVYDDRAR EFGDHDVDFL
DSVATILATA LERRRYERRL NEAVRDLEAS NERLEQFAYA ASHDLQEPLR MVSSYLELLE
DRYGDRLDED AEEFLAYAVD GAERMREMID GLLAYSRIDS QGDPFEPVAL EDVLDDVLTD
LQVMIERHDA EITTEPLPTI QGDSSQLRQL FQNLLSNAIE YSGDEPPRIH VSAERDGDRW
RLSVRDEGIG LDPEAADRIF QVFQRLHGTD EYDGTGIGLA ICRRIVERHG GEIRVDSEPG
DGATFTFTLP ATEP
//
