ID L0KA91_HALHC Unreviewed; 461 AA.
AC L0KA91;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=NADPH-dependent glutamate synthase, homotetrameric {ECO:0000313|EMBL:AGB41023.1};
GN OrderedLocusNames=Halha_1063 {ECO:0000313|EMBL:AGB41023.1};
OS Halobacteroides halobius (strain ATCC 35273 / DSM 5150 / MD-1).
OC Bacteria; Bacillota; Clostridia; Halanaerobiales; Halobacteroidaceae;
OC Halobacteroides.
OX NCBI_TaxID=748449 {ECO:0000313|EMBL:AGB41023.1, ECO:0000313|Proteomes:UP000010880};
RN [1] {ECO:0000313|Proteomes:UP000010880}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35273 / DSM 5150 / MD-1
RC {ECO:0000313|Proteomes:UP000010880};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Gu W.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Tindall B., Pomrenke H., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "The complete genome of Halobacteroides halobius DSM 5150.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003359; AGB41023.1; -; Genomic_DNA.
DR RefSeq; WP_015326748.1; NC_019978.1.
DR AlphaFoldDB; L0KA91; -.
DR STRING; 748449.Halha_1063; -.
DR KEGG; hhl:Halha_1063; -.
DR PATRIC; fig|748449.3.peg.1018; -.
DR eggNOG; COG0493; Bacteria.
DR HOGENOM; CLU_000422_3_3_9; -.
DR OrthoDB; 9803192at2; -.
DR Proteomes; UP000010880; Chromosome.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR009051; Helical_ferredxn.
DR InterPro; IPR006004; SudA-like.
DR NCBIfam; TIGR01316; gltA; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000010880}.
FT DOMAIN 19..127
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 139..445
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 461 AA; 50523 MW; CD54BCDE37224E95 CRC64;
MSQEEVKYEM PEQDPVERTD NFSEVALGYD EETAIKEAER CLQCSNPKCK TGCPVEVDIP
EFIELVAEGK FEKAAKKVKE KNNLPAICGR VCPQEEQCEA ECIVGIKNEP VGIGRLERFV
ADYIRDSEKV KPVKQDKGKV AVVGAGPAGL TAGADLAKMG YQVTIFESFH KPGGVLTYGI
PEFRLPKEIV QDEVEKIKDL GVEIKLNKVV GKIKGVDELF AEGYDAVFVG TGAGLPKFLG
LEGENLNGVY SANEFLTRVN LMKAYKFPKY KTPVHVGDKV AVVGAGNVAM DAARTALRLG
AKESMIVYRR GREEMPAREE EIHHAQEEGV EFKLLNNPTR ILGDQDGFVR GMECVKMELG
ERDESGRRRP IAIEGSEFEI DVDTVIMAIG QNPNPILLQD TPEIKTTDWG TIKTDESKET
SKEGVFAGGD VVTGAATVIE AMGAGKQAAQ SIDQYIKSRK K
//
