ID L0KKZ4_MESAW Unreviewed; 347 AA.
AC L0KKZ4;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Zn-dependent alcohol dehydrogenase {ECO:0000313|EMBL:AGB46077.1};
GN OrderedLocusNames=Mesau_03718 {ECO:0000313|EMBL:AGB46077.1};
OS Mesorhizobium australicum (strain HAMBI 3006 / LMG 24608 / WSM2073).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Mesorhizobium.
OX NCBI_TaxID=754035 {ECO:0000313|EMBL:AGB46077.1, ECO:0000313|Proteomes:UP000010998};
RN [1] {ECO:0000313|Proteomes:UP000010998}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 24608 / HAMBI 3006 / WSM2073
RC {ECO:0000313|Proteomes:UP000010998};
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Gu W., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Pagani I., Reeve W.G., Howieson J.G., Tiwari R.P.,
RA O'Hara G.W., Atkins C.A., Ronson C.W., Nandasena K.G., Woyke T.;
RT "Complete sequence of Mesorhizobium australicum WSM2073.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
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DR EMBL; CP003358; AGB46077.1; -; Genomic_DNA.
DR RefSeq; WP_015317494.1; NC_019973.1.
DR AlphaFoldDB; L0KKZ4; -.
DR STRING; 754035.Mesau_03718; -.
DR KEGG; mam:Mesau_03718; -.
DR eggNOG; COG1064; Bacteria.
DR HOGENOM; CLU_026673_11_2_5; -.
DR OrthoDB; 9773078at2; -.
DR Proteomes; UP000010998; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR CDD; cd08260; Zn_ADH6; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43401:SF5; ALCOHOL DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR43401; L-THREONINE 3-DEHYDROGENASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000010998};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 10..343
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 347 AA; 37108 MW; 968D67216484EB43 CRC64;
MKAVVFEKFG EAPTIQTVPD PKPAADGVVI KVEATGLCRS DWHGWMGHDA DIRLPHVPGH
ELAGVVVAAG KHVTRWKAGE RVTVPFAVGC GHCFECTSGN HQVCEHQSQP GFNTWGSFAE
YVAIEHADTN LVRLPDEMEF ATAASLGCRF VTSFRAIVDQ GRVKPGEWVA VHGCGGVGLS
AIMIASSMGA NVIAIDLTEE KLDFAKQIGA VATINASTTP NVVKAVKQIT NGGAHMSMDA
LGHPTTSFNS IANLRRRGRH VQVGLMLGEH ARPQVPMDKV IAFELEILGS HGMQAYRYPA
MMEMIRHGKL KPELLVGKKI SLDEAPAALM AMGGFEGIGI GVVTKFS
//
