ID L0KVC1_METHD Unreviewed; 655 AA.
AC L0KVC1;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN OrderedLocusNames=Metho_0372 {ECO:0000313|EMBL:AGB48645.1};
OS Methanomethylovorans hollandica (strain DSM 15978 / NBRC 107637 / DMS1).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanomethylovorans.
OX NCBI_TaxID=867904 {ECO:0000313|EMBL:AGB48645.1, ECO:0000313|Proteomes:UP000010866};
RN [1] {ECO:0000313|Proteomes:UP000010866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15978 / NBRC 107637 / DMS1
RC {ECO:0000313|Proteomes:UP000010866};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Held B.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Spring S., Schroeder M., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome of Methanomethylovorans hollandica DSM
RT 15978.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP003362; AGB48645.1; -; Genomic_DNA.
DR RefSeq; WP_015323814.1; NC_019977.1.
DR AlphaFoldDB; L0KVC1; -.
DR STRING; 867904.Metho_0372; -.
DR GeneID; 14407478; -.
DR KEGG; mhz:Metho_0372; -.
DR HOGENOM; CLU_412593_0_0_2; -.
DR OrthoDB; 3369at2157; -.
DR Proteomes; UP000010866; Chromosome.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43711:SF24; SENSOR HISTIDINE KINASE RPPB; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08448; PAS_4; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000010866}.
FT DOMAIN 208..258
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 298..369
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 372..424
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 442..653
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 655 AA; 74347 MW; ED3082EB6B909ABF CRC64;
MKGMINYRKN AEIECICKIS DIIANSNDFK YVMQQTAEAL PSGFQFPSIT CIRITINNRT
FKNSHFKITH RKLSCSCTGQ DSAVISIEAF YREERPEADE GPFLSGEKTM LFSVCNCLKC
FYERVDMLQL LAESEEKCKA FMNNALDGMM VLDFKGNILL YNMALARMFE VDDPKSSIGY
SILEYICEEY KLKAIKDQLN VMRGKGGYLS TYKVRSRKGR EFWVEGLGTK ILYNDNLANI
VVIRDITERM VAEEKLISYR QNINKLVLER SINVSYANEK LKEDVKIWQH INHILVHETN
KLSEYLGSIG VMVVVLGQDC HVSFINKKGC EILGYNEDGI VGQDWIESFV PDNYRDHTKD
LLLKCLSGNC VTKCEYPVLR FYGEDRMILW ANVPLVDENE NIIGIVSTGE DVTDLRDSQE
ALQQYVDDLK KSNEFKMLFI DILRHDLLNP ATIIKGYSEL LLERITTDEE KSIIKTIYAQ
NENLIQIINT ASMLGKLEST DMVSFENLDL LDLLKKVSSG FTPLLDKKGI TVEYPARDSC
PADVNPMIEE AFSNLISNAI KFSPYGGKLI LDIEDAGPSW KITFTDFGMG ISDENKDAIF
RRFKQVSTEG TKGSGLGLAI VKKIIELHHG EVGVYDNPSG SGAVFWIKLN KRQSF
//
