ID L0KYP3_METHD Unreviewed; 404 AA.
AC L0KYP3;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=2-oxoacid:ferredoxin oxidoreductase, alpha subunit {ECO:0000313|EMBL:AGB50582.1};
GN OrderedLocusNames=Metho_2440 {ECO:0000313|EMBL:AGB50582.1};
OS Methanomethylovorans hollandica (strain DSM 15978 / NBRC 107637 / DMS1).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanomethylovorans.
OX NCBI_TaxID=867904 {ECO:0000313|EMBL:AGB50582.1, ECO:0000313|Proteomes:UP000010866};
RN [1] {ECO:0000313|Proteomes:UP000010866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15978 / NBRC 107637 / DMS1
RC {ECO:0000313|Proteomes:UP000010866};
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Held B.,
RA Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Spring S., Schroeder M., Brambilla E., Klenk H.-P.,
RA Eisen J.A.;
RT "Complete sequence of chromosome of Methanomethylovorans hollandica DSM
RT 15978.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma
CC chain. {ECO:0000256|ARBA:ARBA00011595}.
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DR EMBL; CP003362; AGB50582.1; -; Genomic_DNA.
DR RefSeq; WP_015325747.1; NC_019977.1.
DR AlphaFoldDB; L0KYP3; -.
DR STRING; 867904.Metho_2440; -.
DR GeneID; 14408519; -.
DR KEGG; mhz:Metho_2440; -.
DR HOGENOM; CLU_002569_5_0_2; -.
DR OrthoDB; 372068at2157; -.
DR Proteomes; UP000010866; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR NCBIfam; NF040682; PorA_Arch; 1.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR PANTHER; PTHR32154:SF0; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000010866}.
FT DOMAIN 24..247
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 271..374
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
SQ SEQUENCE 404 AA; 44987 MW; F0B3CACDACEF57E5 CRC64;
MTTKGKLEKE KMVVVEGSYA VAHAVKICRP NVISAYPITP QTHIVEGLSK FMADGEIQNC
EYINVESEFS ALSALVGSSA VGARCYSATT SQGLELMHEV LFNVSGMRLP IVMTVVNRAV
SAPINIWNDH QDAISQRDTG WIQLYAEDLQ EAADMTAQAF KIAEDKEVLM PVMACMDGFI
LSHVYEPVIL LEQELTDEYL PTYEPLNTLD PKKPMSFGTL ADPNCYTEFR YLQQKAMENA
LKKIEDAANE FYDVFGRYYG GLIDEYQTED ADIILMAMGS IVGTIKDTID KLRQKGVKVG
LLKVRSFRPF PAEAIREAIK DAKVVAVLDK NISLGLNEGA LFTETKSCLY NTKNRVPVVG
YMIGHGGRDI RMSTIENIIS EAQEVMKTGI KLESQFTDVR EELL
//
