ID L0LY39_ENTBF Unreviewed; 257 AA.
AC L0LY39;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=HTH-type transcriptional repressor NanR {ECO:0000256|HAMAP-Rule:MF_01236};
GN Name=nanR {ECO:0000256|HAMAP-Rule:MF_01236};
GN OrderedLocusNames=D782_0475 {ECO:0000313|EMBL:AGB76538.1};
OS Enterobacteriaceae bacterium (strain FGI 57).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae.
OX NCBI_TaxID=693444 {ECO:0000313|EMBL:AGB76538.1, ECO:0000313|Proteomes:UP000011002};
RN [1] {ECO:0000313|EMBL:AGB76538.1, ECO:0000313|Proteomes:UP000011002}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGI 57 {ECO:0000313|EMBL:AGB76538.1,
RC ECO:0000313|Proteomes:UP000011002};
RX PubMed=23469353; DOI=10.1128/genomeA.00238-12;
RA Aylward F.O., Tremmel D.M., Bruce D.C., Chain P., Chen A.,
RA Walston Davenport K., Detter C., Han C.S., Han J., Huntemann M.,
RA Ivanova N.N., Kyrpides N.C., Markowitz V., Mavrommatis K., Nolan M.,
RA Pagani I., Pati A., Pitluck S., Deshpande S., Goodwin L., Woyke T.,
RA Currie C.R.;
RT "Complete genome of Enterobacteriaceae bacterium strain FGI 57, a strain
RT associated with leaf-cutter ant fungus gardens.";
RL Genome Announc. 1:E00238-12(2013).
CC -!- FUNCTION: Transcriptional repressor that controls expression of the
CC genes required for the catabolism of sialic acids. {ECO:0000256|HAMAP-
CC Rule:MF_01236}.
CC -!- SIMILARITY: Belongs to the NanR family. {ECO:0000256|HAMAP-
CC Rule:MF_01236}.
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DR EMBL; CP003938; AGB76538.1; -; Genomic_DNA.
DR AlphaFoldDB; L0LY39; -.
DR STRING; 693444.D782_0475; -.
DR KEGG; ebf:D782_0475; -.
DR PATRIC; fig|693444.3.peg.462; -.
DR eggNOG; COG2186; Bacteria.
DR HOGENOM; CLU_017584_9_1_6; -.
DR OrthoDB; 7005926at2; -.
DR Proteomes; UP000011002; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 1.20.120.530; GntR ligand-binding domain-like; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR HAMAP; MF_01236; HTH_NanR; 1.
DR InterPro; IPR011711; GntR_C.
DR InterPro; IPR008920; TF_FadR/GntR_C.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR023730; Tscrpt_reg_NanR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43537:SF23; HTH-TYPE TRANSCRIPTIONAL REPRESSOR NANR; 1.
DR PANTHER; PTHR43537; TRANSCRIPTIONAL REGULATOR, GNTR FAMILY; 1.
DR Pfam; PF07729; FCD; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00895; FCD; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF48008; GntR ligand-binding domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_01236}; Reference proteome {ECO:0000313|Proteomes:UP000011002};
KW Repressor {ECO:0000256|HAMAP-Rule:MF_01236};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_01236};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015, ECO:0000256|HAMAP-
KW Rule:MF_01236}.
FT DOMAIN 24..92
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 257 AA; 28896 MW; 8F06CA6E6F77A35B CRC64;
MSAFDSNSED TIGNSLRRRP LARKKLSEMV EEELEQMIRR REFGEGEQLP SERELMAFFN
VGRPSVREAL AALKRKGLVQ INNGERARVS RPSADTIIGE LSGMAKDFLS HPGGIAHFEQ
LRLFFESSLV RYAAEHATDE QIALLSKALE INSQALDDNA QFIRSDVDFH RVLAEIPGNP
IFMAIHVALL DWLIAARPKV ADQELHEHNS VSYQQHIAIV DAIRAHDPDE ADRALQTHLN
SVSATWHAFG KAKKSRK
//
