ID L0M699_ENTBF Unreviewed; 359 AA.
AC L0M699;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=RND family efflux transporter, MFP subunit {ECO:0000313|EMBL:AGB79429.1};
GN OrderedLocusNames=D782_3500 {ECO:0000313|EMBL:AGB79429.1};
OS Enterobacteriaceae bacterium (strain FGI 57).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae.
OX NCBI_TaxID=693444 {ECO:0000313|EMBL:AGB79429.1, ECO:0000313|Proteomes:UP000011002};
RN [1] {ECO:0000313|EMBL:AGB79429.1, ECO:0000313|Proteomes:UP000011002}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGI 57 {ECO:0000313|EMBL:AGB79429.1,
RC ECO:0000313|Proteomes:UP000011002};
RX PubMed=23469353; DOI=10.1128/genomeA.00238-12;
RA Aylward F.O., Tremmel D.M., Bruce D.C., Chain P., Chen A.,
RA Walston Davenport K., Detter C., Han C.S., Han J., Huntemann M.,
RA Ivanova N.N., Kyrpides N.C., Markowitz V., Mavrommatis K., Nolan M.,
RA Pagani I., Pati A., Pitluck S., Deshpande S., Goodwin L., Woyke T.,
RA Currie C.R.;
RT "Complete genome of Enterobacteriaceae bacterium strain FGI 57, a strain
RT associated with leaf-cutter ant fungus gardens.";
RL Genome Announc. 1:E00238-12(2013).
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP003938; AGB79429.1; -; Genomic_DNA.
DR AlphaFoldDB; L0M699; -.
DR STRING; 693444.D782_3500; -.
DR KEGG; ebf:D782_3500; -.
DR PATRIC; fig|693444.3.peg.3346; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_1_2_6; -.
DR OrthoDB; 9800613at2; -.
DR Proteomes; UP000011002; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0009636; P:response to toxic substance; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30158; ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER; 1.
DR PANTHER; PTHR30158:SF3; MULTIDRUG EFFLUX PUMP SUBUNIT ACRA-RELATED; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000011002};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..359
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003945597"
FT DOMAIN 54..273
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 94..121
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 359 AA; 38992 MW; 32EC527E80442CD9 CRC64;
MPKTIRHAVL SCVLIACSLS PAFASAIAVR VSTVENVSHA AERQIPGRIE AIHTVELRAR
IEGAIHTIHF HDGQYVKQGD LLFELDDAEH QAALRLAQAE LNSAQATLRQ AQQVLNRYQS
LKSSDAISRN DVDNARMQRD VASAAVAQAS ARVEARKVTL GYTRITSPVN GRIGHTQFHV
GSLVSPSSGT LVDVVQLDPI RIAFALEEQV FASKVDRHAD VGELKKAWLA QIEVGDARED
GVLTSVDNRI DPRTASVTLR AEFANPRHRL LPGGSINVWL RPQEAQQVVT LPAAAVMQNG
DGFYTWVISK DNTAEKRPLK LAGQIGQAYQ VLEGVKAGER VVVEGVQRVQ NGAAVQVLN
//
