ID L0M7C8_ENTBF Unreviewed; 415 AA.
AC L0M7C8;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Small-conductance mechanosensitive channel {ECO:0000313|EMBL:AGB79207.1};
GN OrderedLocusNames=D782_3271 {ECO:0000313|EMBL:AGB79207.1};
OS Enterobacteriaceae bacterium (strain FGI 57).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae.
OX NCBI_TaxID=693444 {ECO:0000313|EMBL:AGB79207.1, ECO:0000313|Proteomes:UP000011002};
RN [1] {ECO:0000313|EMBL:AGB79207.1, ECO:0000313|Proteomes:UP000011002}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGI 57 {ECO:0000313|EMBL:AGB79207.1,
RC ECO:0000313|Proteomes:UP000011002};
RX PubMed=23469353; DOI=10.1128/genomeA.00238-12;
RA Aylward F.O., Tremmel D.M., Bruce D.C., Chain P., Chen A.,
RA Walston Davenport K., Detter C., Han C.S., Han J., Huntemann M.,
RA Ivanova N.N., Kyrpides N.C., Markowitz V., Mavrommatis K., Nolan M.,
RA Pagani I., Pati A., Pitluck S., Deshpande S., Goodwin L., Woyke T.,
RA Currie C.R.;
RT "Complete genome of Enterobacteriaceae bacterium strain FGI 57, a strain
RT associated with leaf-cutter ant fungus gardens.";
RL Genome Announc. 1:E00238-12(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
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DR EMBL; CP003938; AGB79207.1; -; Genomic_DNA.
DR AlphaFoldDB; L0M7C8; -.
DR STRING; 693444.D782_3271; -.
DR KEGG; ebf:D782_3271; -.
DR PATRIC; fig|693444.3.peg.3119; -.
DR eggNOG; COG0668; Bacteria.
DR HOGENOM; CLU_045354_1_0_6; -.
DR OrthoDB; 9775207at2; -.
DR Proteomes; UP000011002; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0008381; F:mechanosensitive monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0071470; P:cellular response to osmotic stress; IEA:InterPro.
DR Gene3D; 2.30.30.60; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR030192; YbdG.
DR PANTHER; PTHR30414:SF0; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL YBDG; 1.
DR PANTHER; PTHR30414; UNCHARACTERIZED; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000011002};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 184..252
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 329..395
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 415 AA; 46503 MW; A115A55A6736B7A4 CRC64;
MQELIAQVEE LGIEINHTSS LVIIFGIILL TAIVVHIILH RIVLRTFERR AQASSKLWLQ
IITQNKLFHR LAFTLQGIIV NVQAVLWLQK GSDAAQILTT CAQLWVMLYA LLSFFSLLDV
IFNLSQKFSA ASQLPLKGIF QGVKLVSAIL VGILIISLLL GQSPAILISG LGAMAAVLML
VFKDPILGLV AGIQLSANDM LKLGDWLEMP KYGADGAVTD IGLTTVKVRN WDNTITTIPT
WSLVSDSFKN WSGMSASGGR RIKRSINIDT TSVHFLDEQE QQRLIQAKLL KPYMDSRHQE
IDEWNREHGS EASVLNLRKM TNVGTFRAYL NEYLRNHPRI RKDMTLMVRQ LAPDNNGLPM
EIYCFTNTVV WAEYESIQAD IFDHIFAVVE EFGLRVYQSP TGNDIRSLAG AIQAQ
//
