ID L1IEB2_GUITC Unreviewed; 1079 AA.
AC L1IEB2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 54.
DE SubName: Full=Exportin-1 {ECO:0000313|EMBL:EKX34427.1};
GN Name=Exportin1 {ECO:0000313|EMBL:EKX34427.1};
GN ORFNames=GUITHDRAFT_80578 {ECO:0000313|EMBL:EKX34427.1};
OS Guillardia theta (strain CCMP2712) (Cryptophyte).
OC Eukaryota; Cryptophyceae; Pyrenomonadales; Geminigeraceae; Guillardia.
OX NCBI_TaxID=905079 {ECO:0000313|EMBL:EKX34427.1};
RN [1] {ECO:0000313|EMBL:EKX34427.1, ECO:0000313|Proteomes:UP000011087}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP2712 {ECO:0000313|EMBL:EKX34427.1,
RC ECO:0000313|Proteomes:UP000011087};
RX PubMed=23201678; DOI=10.1038/nature11681;
RG DOE Joint Genome Institute;
RA Curtis B.A., Tanifuji G., Burki F., Gruber A., Irimia M., Maruyama S.,
RA Arias M.C., Ball S.G., Gile G.H., Hirakawa Y., Hopkins J.F., Kuo A.,
RA Rensing S.A., Schmutz J., Symeonidi A., Elias M., Eveleigh R.J.,
RA Herman E.K., Klute M.J., Nakayama T., Obornik M., Reyes-Prieto A.,
RA Armbrust E.V., Aves S.J., Beiko R.G., Coutinho P., Dacks J.B.,
RA Durnford D.G., Fast N.M., Green B.R., Grisdale C.J., Hempel F.,
RA Henrissat B., Hoppner M.P., Ishida K., Kim E., Koreny L., Kroth P.G.,
RA Liu Y., Malik S.B., Maier U.G., McRose D., Mock T., Neilson J.A.,
RA Onodera N.T., Poole A.M., Pritham E.J., Richards T.A., Rocap G., Roy S.W.,
RA Sarai C., Schaack S., Shirato S., Slamovits C.H., Spencer D.F., Suzuki S.,
RA Worden A.Z., Zauner S., Barry K., Bell C., Bharti A.K., Crow J.A.,
RA Grimwood J., Kramer R., Lindquist E., Lucas S., Salamov A., McFadden G.I.,
RA Lane C.E., Keeling P.J., Gray M.W., Grigoriev I.V., Archibald J.M.;
RT "Algal genomes reveal evolutionary mosaicism and the fate of
RT nucleomorphs.";
RL Nature 492:59-65(2012).
RN [2] {ECO:0000313|Proteomes:UP000011087}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP2712 {ECO:0000313|Proteomes:UP000011087};
RA Kuo A., Curtis B.A., Tanifuji G., Burki F., Gruber A., Irimia M.,
RA Maruyama S., Arias M.C., Ball S.G., Gile G.H., Hirakawa Y., Hopkins J.F.,
RA Rensing S.A., Schmutz J., Symeonidi A., Elias M., Eveleigh R.J.,
RA Herman E.K., Klute M.J., Nakayama T., Obornik M., Reyes-Prieto A.,
RA Armbrust E.V., Aves S.J., Beiko R.G., Coutinho P., Dacks J.B.,
RA Durnford D.G., Fast N.M., Green B.R., Grisdale C., Hempe F., Henrissat B.,
RA Hoppner M.P., Ishida K.-I., Kim E., Koreny L., Kroth P.G., Liu Y.,
RA Malik S.-B., Maier U.G., McRose D., Mock T., Neilson J.A., Onodera N.T.,
RA Poole A.M., Pritham E.J., Richards T.A., Rocap G., Roy S.W., Sarai C.,
RA Schaack S., Shirato S., Slamovits C.H., Spencer D.F., Suzuki S.,
RA Worden A.Z., Zauner S., Barry K., Bell C., Bharti A.K., Crow J.A.,
RA Grimwood J., Kramer R., Lindquist E., Lucas S., Salamov A., McFadden G.I.,
RA Lane C.E., Keeling P.J., Gray M.W., Grigoriev I.V., Archibald J.M.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblProtists:EKX34427}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH993110; EKX34427.1; -; Genomic_DNA.
DR RefSeq; XP_005821407.1; XM_005821350.1.
DR AlphaFoldDB; L1IEB2; -.
DR STRING; 905079.L1IEB2; -.
DR PaxDb; 55529-EKX34427; -.
DR EnsemblProtists; EKX34427; EKX34427; GUITHDRAFT_80578.
DR GeneID; 17291144; -.
DR KEGG; gtt:GUITHDRAFT_80578; -.
DR eggNOG; KOG2020; Eukaryota.
DR HOGENOM; CLU_011906_0_0_1; -.
DR OMA; WAFKHNN; -.
DR OrthoDB; 169519at2759; -.
DR Proteomes; UP000011087; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR041123; CRM1_repeat.
DR InterPro; IPR041235; Exp1_repeat_2.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR InterPro; IPR014877; XPO1_C_dom.
DR InterPro; IPR040485; XPO1_repeat_3.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF08767; CRM1_C; 1.
DR Pfam; PF18777; CRM1_repeat; 1.
DR Pfam; PF18784; CRM1_repeat_2; 1.
DR Pfam; PF18787; CRM1_repeat_3; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM01102; CRM1_C; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000011087};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 39..105
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 1079 AA; 124637 MW; 6843182F8F6D63BE CRC64;
MSSELEKLLD FGSPLDVALL DQVVIAMYTC RDEAQRKQIN AFMTAFQEHP QAWTRVDTIL
EQTQCDQSRF FALATLETCV KQRWKVLPQD QREAIKAYIV NVIVRYSSDE ATLVRTKTQL
GKLNLILVQI LKQEWPHNWK DFIPQIVESG KTNETLCGNN MQILKLLSEE VFEFSLKQLT
SKKIDDLKER LTQEFELIYQ LCEFVMQNAK NVITLQTTLQ CFLRFLFWVP LYYVFETPLI
EMLLHKFFPQ PQFRSDALQC LTEIAVIEPK GIDPRYHPKI QKTYADFITN LSNIVQPNAI
KQYYEEGESG EEFVQRLTLF LCTILKTHIG ILETQELVPY LIQGLQYLVF ISEVDDDEIF
KICTEYWNFL ADDLYHKEVL LQRMPIPTFC QLMPNQNPRL QTYAPILTEV RRILIERMPK
PEEVLVVEDE NGQVVKEHLK DVEVVALHKT VRETLVYLTH LDHQQTEEIM IEKLGLQVHP
APGGPGWSRQ GLSTLCWAIG SISGAMREDD EKKFLVHVIK DLLGLCEIVR GKDNKAVIAS
NIMYVVGQYP RFLRAHWKFL KTVVNKLFEF MHETHPGVQD MACETFLKIC QRCKQQFVKH
QPQEPAPFID QLLIGPHSTV ADIGSTIADL EAHQINMFYE AVGYIVAAEL TPERRDQIVQ
VLFKIPNQRW TQIIGSAMQD PNLLQQQETM REIAKVLQIN VRVSSSLGNP YIIQLEYIFE
RMLQVYKMYS EQISQAVVGN PLSAKTSGVR LMRAVKRETL RLIETTVEKS EEMPRIVAHF
VPPLVDYVLA DYQSNHPETR DPEVLSVFAA IIRRAGDSIT DQVPRVLGAV FECTLAMITT
NMEDYPEHRI NFFNLLKEIN HHCFRAFFQV PGEVFKVLID SIVWAIKHRE RNIAETGLTI
LLEMLRNLDG LQDIAAQFYV QFLLNLLHEI FTVLTDKEHE PGFKLQCAIL QHMIYRVMAG
VPNTPLFNPS EYPGVADNKS FVKQKLLAML SEGFSERMTQ KQLTEFVENL FGPEKDIAAF
QTLVRDFLIQ IKEYSSDQWT DSSLALQLEQ EQKEAERKRV TPSRGAAAWA GWLTSWCAG
//
