ID L1ILM8_GUITC Unreviewed; 1757 AA.
AC L1ILM8;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GUITHDRAFT_145261 {ECO:0000313|EMBL:EKX37161.1};
OS Guillardia theta (strain CCMP2712) (Cryptophyte).
OC Eukaryota; Cryptophyceae; Pyrenomonadales; Geminigeraceae; Guillardia.
OX NCBI_TaxID=905079 {ECO:0000313|EMBL:EKX37161.1};
RN [1] {ECO:0000313|EMBL:EKX37161.1, ECO:0000313|Proteomes:UP000011087}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP2712 {ECO:0000313|EMBL:EKX37161.1,
RC ECO:0000313|Proteomes:UP000011087};
RX PubMed=23201678; DOI=10.1038/nature11681;
RG DOE Joint Genome Institute;
RA Curtis B.A., Tanifuji G., Burki F., Gruber A., Irimia M., Maruyama S.,
RA Arias M.C., Ball S.G., Gile G.H., Hirakawa Y., Hopkins J.F., Kuo A.,
RA Rensing S.A., Schmutz J., Symeonidi A., Elias M., Eveleigh R.J.,
RA Herman E.K., Klute M.J., Nakayama T., Obornik M., Reyes-Prieto A.,
RA Armbrust E.V., Aves S.J., Beiko R.G., Coutinho P., Dacks J.B.,
RA Durnford D.G., Fast N.M., Green B.R., Grisdale C.J., Hempel F.,
RA Henrissat B., Hoppner M.P., Ishida K., Kim E., Koreny L., Kroth P.G.,
RA Liu Y., Malik S.B., Maier U.G., McRose D., Mock T., Neilson J.A.,
RA Onodera N.T., Poole A.M., Pritham E.J., Richards T.A., Rocap G., Roy S.W.,
RA Sarai C., Schaack S., Shirato S., Slamovits C.H., Spencer D.F., Suzuki S.,
RA Worden A.Z., Zauner S., Barry K., Bell C., Bharti A.K., Crow J.A.,
RA Grimwood J., Kramer R., Lindquist E., Lucas S., Salamov A., McFadden G.I.,
RA Lane C.E., Keeling P.J., Gray M.W., Grigoriev I.V., Archibald J.M.;
RT "Algal genomes reveal evolutionary mosaicism and the fate of
RT nucleomorphs.";
RL Nature 492:59-65(2012).
RN [2] {ECO:0000313|Proteomes:UP000011087}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP2712 {ECO:0000313|Proteomes:UP000011087};
RA Kuo A., Curtis B.A., Tanifuji G., Burki F., Gruber A., Irimia M.,
RA Maruyama S., Arias M.C., Ball S.G., Gile G.H., Hirakawa Y., Hopkins J.F.,
RA Rensing S.A., Schmutz J., Symeonidi A., Elias M., Eveleigh R.J.,
RA Herman E.K., Klute M.J., Nakayama T., Obornik M., Reyes-Prieto A.,
RA Armbrust E.V., Aves S.J., Beiko R.G., Coutinho P., Dacks J.B.,
RA Durnford D.G., Fast N.M., Green B.R., Grisdale C., Hempe F., Henrissat B.,
RA Hoppner M.P., Ishida K.-I., Kim E., Koreny L., Kroth P.G., Liu Y.,
RA Malik S.-B., Maier U.G., McRose D., Mock T., Neilson J.A., Onodera N.T.,
RA Poole A.M., Pritham E.J., Richards T.A., Rocap G., Roy S.W., Sarai C.,
RA Schaack S., Shirato S., Slamovits C.H., Spencer D.F., Suzuki S.,
RA Worden A.Z., Zauner S., Barry K., Bell C., Bharti A.K., Crow J.A.,
RA Grimwood J., Kramer R., Lindquist E., Lucas S., Salamov A., McFadden G.I.,
RA Lane C.E., Keeling P.J., Gray M.W., Grigoriev I.V., Archibald J.M.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblProtists:EKX37161}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (MAR-2016) to UniProtKB.
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DR EMBL; JH993063; EKX37161.1; -; Genomic_DNA.
DR RefSeq; XP_005824141.1; XM_005824084.1.
DR STRING; 905079.L1ILM8; -.
DR PaxDb; 55529-EKX37161; -.
DR EnsemblProtists; EKX37161; EKX37161; GUITHDRAFT_145261.
DR GeneID; 17293847; -.
DR KEGG; gtt:GUITHDRAFT_145261; -.
DR eggNOG; KOG1217; Eukaryota.
DR HOGENOM; CLU_239203_0_0_1; -.
DR OMA; CDEQLAY; -.
DR OrthoDB; 23612at2759; -.
DR Proteomes; UP000011087; Unassembled WGS sequence.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 14.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR PANTHER; PTHR46104:SF6; -; 1.
DR PANTHER; PTHR46104; GENE 9195-RELATED-RELATED; 1.
DR Pfam; PF07699; Ephrin_rec_like; 7.
DR SMART; SM00181; EGF; 9.
DR SMART; SM01411; Ephrin_rec_like; 22.
DR SMART; SM00208; TNFR; 5.
DR SUPFAM; SSF57184; Growth factor receptor domain; 9.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000011087};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..1757
FT /note="Tyrosine-protein kinase ephrin type A/B receptor-
FT like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008770172"
FT DOMAIN 159..207
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 222..257
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 226..258
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|SMART:SM00208"
FT DOMAIN 273..304
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|SMART:SM00208"
FT DOMAIN 592..644
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 742..791
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 886..920
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|SMART:SM00208"
FT DOMAIN 1081..1133
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 1182..1228
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 1280..1336
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 1338..1380
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|SMART:SM00208"
FT DOMAIN 1413..1461
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT DOMAIN 1414..1447
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|SMART:SM00208"
FT DOMAIN 1630..1684
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT REGION 444..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1757 AA; 183803 MW; 20D2F4AB59F1DCD6 CRC64;
MRGLAVLAYA SLLQLAWLVL LAQGLSCPAG SEPLLSSELV QLVKECNLTS QSPCSLHFPA
LTLSDTSELN VSIYISPHNA SGYFLAASFS MFAFTEKLSR DYLGSNCTEF DVYTWITKTS
DIAPNSELSI RINGSSSNTS SCPSLLARVQ VSYTPACRPC AQGSYAGVNS SSCEACPALS
TSPGGSIALD NCTCQAGYTG KNISDCQGCP AGQFKGLMGF QACDDCPVGT YSQLEGSSAC
TNCPMGMTSV GGTSSCICAG GYVFEAAFRC FPCPAGSFKN ATGNGTCSVC GDGTYASSNG
TVVCLSCPKG SYREKPPQLH GDGRSELSGL LPTQLDGCNG ELNDRLLQPG MTTCAPCDPG
YFSHIASSEC TADVVDVLVE VFVSGDVDAF TLDLQSNLTQ VLSSLFLLPL DLVYFVSSAL
VGGTQSNNLV EQGNVTVSNA SNATELSNST NSSNTTDSFN SSDILSTPPS TTPLPSSSSS
PVVKATWRVM AARSFFASLL QTFDRQQFLR DFNASHVLNI VFTERCGAGR QRNATGSCEA
CPVGTFKNAS DDSQCFPCRS NASTAGEGVI LSTDCLCLPG YKFVSFDSPC EPCSPGSYSN
TLANQDCQLC AANTYNSKLA STSCTACPPR SVSGEGSPSI SSCLCVPGYR PDSTASSFSC
RMCPVNTYKN FTGNTECVSC PPHSVSSMRT VDIKYCRCDF GYTGPNTNCT PCPAGTYKEY
PGPYRSLISR CIPGYGSNLS STCSLCPIGT YKFFVATVEC LTCPGNFSTH QIGSTSCECS
PGFQLEGGNC TRCPQGTWKN YTGNETCSSC PPDSSTVPGA VEITDCICNA GYEWVDNGCS
FCSFGKIRKD LSWSSCQPCP PGRSSNADRT VCTFTGCAQG EWWKNCSEYE NAACMPCTSL
QPCPNGFYWD SCQAWDDAQC RPCTNSKPLN AHFTRPGLPA APTSCPSWAC DQGYEEIGGD
CVACPSGKYS NRGQPSCSSC PGDTDSLLPG QGFCRACKTG FYIESFGMDG HAICTPCPDN
STTSPNQNIY SFSTCHCSRG YMGFSWKCQP CQPGTYKPNV TGSTDLQLYY SGFQLLDLCV
KCPPMTFNDL PGQSSASSCL PCLPGSTAPE GSASCSCPAG QYDTDPTGQA SCLPCPSNTF
NDHAGQLGVS SCLPCPNNSY SAEGQVACFC NYGYFSAGQC LGCPAGKYKQ DVGCFDCPAF
ATSNEGSVSS SQCFCRGGYY GSPSSSCLIC PLNTTSLPGA AATLSDCICE EGYYGSNTDC
VQCPLLSKSP AGSTVLSSCT CVPGSAGDPG RNISCKLCSA VDPNSYSWES SFNCSCNAGY
YGSFVFVEDR VQVNCSLCPQ GTYSSTPAVT HCTSCPSNKT SQLGSTSLSA CTCPTGTVEA
SGECVVTQRR LLASSDEVSC PPNSSQTMSG SCLCDPGHFS SSGAPPCSPC MEGTVTKFAG
SSSCASCPAG SISIQDRTSC VCPVGQYGQA GSCVRCPSGM LAVAGSDEAS DCECEEGFYL
HEEEEACRRC PEGSSSRRGS VGLGGCACVR GYFGRPWEGR GCSACPANAS SEENSTTAQE
CFCSAGFYAG VGEDLSCSRC PPRSFSLPGS RSISNCMCDE GFYGNLSAHQ DCSPCPANSL
AVGSRLLLSD CLCMEGYFSV PSGRCLACPA NALSSLGSRS IFDCTCNAGY YGTPGVLSSP
PTCKACPAGK YSWGPVRLTE DSCLSCPAHS MSNSSSLSRE DCKCASGYCR GEGESWECTP
CSCPAGLDGK MCLLREL
//
