ID L1IR75_GUITC Unreviewed; 1825 AA.
AC L1IR75;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Roc domain-containing protein {ECO:0000259|PROSITE:PS51424};
GN ORFNames=GUITHDRAFT_115574 {ECO:0000313|EMBL:EKX38310.1};
OS Guillardia theta (strain CCMP2712) (Cryptophyte).
OC Eukaryota; Cryptophyceae; Pyrenomonadales; Geminigeraceae; Guillardia.
OX NCBI_TaxID=905079 {ECO:0000313|EMBL:EKX38310.1};
RN [1] {ECO:0000313|EMBL:EKX38310.1, ECO:0000313|Proteomes:UP000011087}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP2712 {ECO:0000313|EMBL:EKX38310.1,
RC ECO:0000313|Proteomes:UP000011087};
RX PubMed=23201678; DOI=10.1038/nature11681;
RG DOE Joint Genome Institute;
RA Curtis B.A., Tanifuji G., Burki F., Gruber A., Irimia M., Maruyama S.,
RA Arias M.C., Ball S.G., Gile G.H., Hirakawa Y., Hopkins J.F., Kuo A.,
RA Rensing S.A., Schmutz J., Symeonidi A., Elias M., Eveleigh R.J.,
RA Herman E.K., Klute M.J., Nakayama T., Obornik M., Reyes-Prieto A.,
RA Armbrust E.V., Aves S.J., Beiko R.G., Coutinho P., Dacks J.B.,
RA Durnford D.G., Fast N.M., Green B.R., Grisdale C.J., Hempel F.,
RA Henrissat B., Hoppner M.P., Ishida K., Kim E., Koreny L., Kroth P.G.,
RA Liu Y., Malik S.B., Maier U.G., McRose D., Mock T., Neilson J.A.,
RA Onodera N.T., Poole A.M., Pritham E.J., Richards T.A., Rocap G., Roy S.W.,
RA Sarai C., Schaack S., Shirato S., Slamovits C.H., Spencer D.F., Suzuki S.,
RA Worden A.Z., Zauner S., Barry K., Bell C., Bharti A.K., Crow J.A.,
RA Grimwood J., Kramer R., Lindquist E., Lucas S., Salamov A., McFadden G.I.,
RA Lane C.E., Keeling P.J., Gray M.W., Grigoriev I.V., Archibald J.M.;
RT "Algal genomes reveal evolutionary mosaicism and the fate of
RT nucleomorphs.";
RL Nature 492:59-65(2012).
RN [2] {ECO:0000313|Proteomes:UP000011087}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP2712 {ECO:0000313|Proteomes:UP000011087};
RA Kuo A., Curtis B.A., Tanifuji G., Burki F., Gruber A., Irimia M.,
RA Maruyama S., Arias M.C., Ball S.G., Gile G.H., Hirakawa Y., Hopkins J.F.,
RA Rensing S.A., Schmutz J., Symeonidi A., Elias M., Eveleigh R.J.,
RA Herman E.K., Klute M.J., Nakayama T., Obornik M., Reyes-Prieto A.,
RA Armbrust E.V., Aves S.J., Beiko R.G., Coutinho P., Dacks J.B.,
RA Durnford D.G., Fast N.M., Green B.R., Grisdale C., Hempe F., Henrissat B.,
RA Hoppner M.P., Ishida K.-I., Kim E., Koreny L., Kroth P.G., Liu Y.,
RA Malik S.-B., Maier U.G., McRose D., Mock T., Neilson J.A., Onodera N.T.,
RA Poole A.M., Pritham E.J., Richards T.A., Rocap G., Roy S.W., Sarai C.,
RA Schaack S., Shirato S., Slamovits C.H., Spencer D.F., Suzuki S.,
RA Worden A.Z., Zauner S., Barry K., Bell C., Bharti A.K., Crow J.A.,
RA Grimwood J., Kramer R., Lindquist E., Lucas S., Salamov A., McFadden G.I.,
RA Lane C.E., Keeling P.J., Gray M.W., Grigoriev I.V., Archibald J.M.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblProtists:EKX38310}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; JH993050; EKX38310.1; -; Genomic_DNA.
DR RefSeq; XP_005825290.1; XM_005825233.1.
DR STRING; 905079.L1IR75; -.
DR PaxDb; 55529-EKX38310; -.
DR EnsemblProtists; EKX38310; EKX38310; GUITHDRAFT_115574.
DR GeneID; 17295030; -.
DR KEGG; gtt:GUITHDRAFT_115574; -.
DR eggNOG; KOG0619; Eukaryota.
DR HOGENOM; CLU_237519_0_0_1; -.
DR OMA; GAVPWIK; -.
DR OrthoDB; 2970981at2759; -.
DR Proteomes; UP000011087; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd11709; SPRY; 2.
DR Gene3D; 2.60.120.920; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR032171; COR.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020859; ROC_dom.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR48051; -; 1.
DR PANTHER; PTHR48051:SF43; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47-LIKE PROTEIN; 1.
DR Pfam; PF16095; COR; 1.
DR Pfam; PF08477; Roc; 1.
DR Pfam; PF00622; SPRY; 2.
DR Pfam; PF13676; TIR_2; 2.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00369; LRR_TYP; 3.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 2.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS51450; LRR; 2.
DR PROSITE; PS51424; ROC; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000011087};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 658..858
FT /note="Roc"
FT /evidence="ECO:0000259|PROSITE:PS51424"
FT REGION 1529..1550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1825 AA; 207175 MW; 77A64A7D3D93D415 CRC64;
MYEHGFAYCP SKGVKYSSGG KTPYAQRRLK PGDVIACSLD CERREIRYLV NGEDLGVAFG
EEEVTEEAVG EGLRFTVTLG PGQGVKLVKA EEEEEESEGR ERAWEMLSFY YEGEWCYLRA
LDLELLSFAH VIVRLLVNNS QSQGLEVLRL MGENSSFLLY GSNSKEFQMT GSLIDTLLDE
KVLSSTCLSH TKEVTVVEEL IQNLEEVVGQ GLKPWIQLIA HKLVRRRMYE HGFAYCPSKG
VKYSSGGKTP YAQRRLKPGD VIACSLDCER REIRYLVNGE DLGVAFGEEE VTEEAVGEGL
RFTQRSQQSS DDLSRNLKCC VSDFMLDDQV GLSFKQNFQK FFFELEFEAA EATMMIESRS
SIFKASEVCL PLIPSLYIHM WYANKISQLS LVRIQLSDIP AEISILRLQS LDVSENRLNH
LSPSLCLVVT LEILRCNNNF LSILPDDIGL LVNLIKLEAA QNALSSLPDS LFSLARLEDL
DISGPPLPRE RLCRNSTAEL ELDSFLGFFR EVSCWEEIVG RSEQEEMFYR HAQEGVVARE
RLVDLEEEML HKYWRYKGRR HESFSFDPAI LTMRSLRRLS MRNVGIQGRL LIPRHVTTGS
LEEVDLSYNQ ISDVSLTSQS LRGLKRFCLE GNRLLIPEEV KKRGEASVLN FLRGRAEASQ
ESFKLMLFLH GLGGVGKTCL LAALKGKEFD PDGEMTDGIE ISSWKVRVEE EEVQYLKQAL
TESQQNQVSQ RLSRKRIEDL MGVEIEFVVH DFAGQEVYYN SHQLFLHNRA LELVLWDVRR
GFDNSGVCFW LNNIKTCAPR AAIIIVGTKT DEMDTPPLDL HALSQKFPQV KAFHAVSSKT
MRGVEDLRRL LVKQALLEEH VGQSIPHKWS ILEDIIVQEA RSSKTGYVRF PTLREWARLS
AFSSDDAIED AADFLHDIGT IVRFSDEDAR LTGLDDVVIT DKQWLADVMS SIITSKSRVH
VLSHADLSSM WQAFPPDVHS NLIDLLKKFD LLVETDSRSF LVPCLLPLGA PRGEDLEAFT
LIPGERLSLS YRTFALSFCP YGFFNLLQAR LRDLDASRFP WCRVGMWRNG MPIASSYHSR
GVVILHQEEN KVECTFSGEG KDNLISVVSE SIFILLTDKY QVTYDVFLPC QGCLDVCPRA
PHMFSSNVTL KRAMQKHQIF LQCHKEFHNI PVAHYLAAMP HSSRVSQEQL SSVLEGIGLW
KATHRAHVYL SYARGDEEAL RAGLRVKALL LEQLIDVWFP THDSPDAVRA NELALSSATI
VIALITKRYC LPHGLGLKEI QYAVEVKPKP VIPVVVEDES PSFPLAWMTS SVGLHLCGLL
YVDLRARDEE QFSLVARRTQ ALLAASGVRG GRSSEHFDFM ISYSWSNCDN GEEAGEEGDT
RREFWSPRRI KRALEESAGS GKQLRGWIDV EQLGNRPREG LYEGIRRGLT ESQVLVVCMS
NEYAMSRNCS MECRYALLLN KPVLLALVGS DDNSPLPPAW KSTETGLLTS HLWSEISKQE
ELFFDFRRVR SKSQFDAIIS SLKRKIEEMQ RNDQEASETR AGQETSPTTI DLSDSVEEQM
KFGRRMAIQF FRSHSSFGST FPVLWVIQWQ PKAQDTLTAF DAWEDNDYFL RPVSETPDAW
VLVPRARFRI DDARHRIKSL SSLLFLVVRC LAVLQQGVLC SLSKVEDSKG ETSAMKKFLR
YEELEVFLEG SSKGMVGRAE AIRESLQLIH NLVKSDDSWS SSSSELKLEV LPSKEVFWSF
WSKDLVRDTI DADWLVEWTR RSNQLEEGGR RSRPRGVTLD EQVMMAETSV VPSDVTDDQS
NIKRLKQILS RQELLLSKFP QTSIK
//
