ID L1JZL4_GUITC Unreviewed; 1255 AA.
AC L1JZL4;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=PHD-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GUITHDRAFT_132829 {ECO:0000313|EMBL:EKX53777.1};
OS Guillardia theta (strain CCMP2712) (Cryptophyte).
OC Eukaryota; Cryptophyceae; Pyrenomonadales; Geminigeraceae; Guillardia.
OX NCBI_TaxID=905079 {ECO:0000313|EMBL:EKX53777.1};
RN [1] {ECO:0000313|EMBL:EKX53777.1, ECO:0000313|Proteomes:UP000011087}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP2712 {ECO:0000313|EMBL:EKX53777.1,
RC ECO:0000313|Proteomes:UP000011087};
RX PubMed=23201678; DOI=10.1038/nature11681;
RG DOE Joint Genome Institute;
RA Curtis B.A., Tanifuji G., Burki F., Gruber A., Irimia M., Maruyama S.,
RA Arias M.C., Ball S.G., Gile G.H., Hirakawa Y., Hopkins J.F., Kuo A.,
RA Rensing S.A., Schmutz J., Symeonidi A., Elias M., Eveleigh R.J.,
RA Herman E.K., Klute M.J., Nakayama T., Obornik M., Reyes-Prieto A.,
RA Armbrust E.V., Aves S.J., Beiko R.G., Coutinho P., Dacks J.B.,
RA Durnford D.G., Fast N.M., Green B.R., Grisdale C.J., Hempel F.,
RA Henrissat B., Hoppner M.P., Ishida K., Kim E., Koreny L., Kroth P.G.,
RA Liu Y., Malik S.B., Maier U.G., McRose D., Mock T., Neilson J.A.,
RA Onodera N.T., Poole A.M., Pritham E.J., Richards T.A., Rocap G., Roy S.W.,
RA Sarai C., Schaack S., Shirato S., Slamovits C.H., Spencer D.F., Suzuki S.,
RA Worden A.Z., Zauner S., Barry K., Bell C., Bharti A.K., Crow J.A.,
RA Grimwood J., Kramer R., Lindquist E., Lucas S., Salamov A., McFadden G.I.,
RA Lane C.E., Keeling P.J., Gray M.W., Grigoriev I.V., Archibald J.M.;
RT "Algal genomes reveal evolutionary mosaicism and the fate of
RT nucleomorphs.";
RL Nature 492:59-65(2012).
RN [2] {ECO:0000313|Proteomes:UP000011087}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP2712 {ECO:0000313|Proteomes:UP000011087};
RA Kuo A., Curtis B.A., Tanifuji G., Burki F., Gruber A., Irimia M.,
RA Maruyama S., Arias M.C., Ball S.G., Gile G.H., Hirakawa Y., Hopkins J.F.,
RA Rensing S.A., Schmutz J., Symeonidi A., Elias M., Eveleigh R.J.,
RA Herman E.K., Klute M.J., Nakayama T., Obornik M., Reyes-Prieto A.,
RA Armbrust E.V., Aves S.J., Beiko R.G., Coutinho P., Dacks J.B.,
RA Durnford D.G., Fast N.M., Green B.R., Grisdale C., Hempe F., Henrissat B.,
RA Hoppner M.P., Ishida K.-I., Kim E., Koreny L., Kroth P.G., Liu Y.,
RA Malik S.-B., Maier U.G., McRose D., Mock T., Neilson J.A., Onodera N.T.,
RA Poole A.M., Pritham E.J., Richards T.A., Rocap G., Roy S.W., Sarai C.,
RA Schaack S., Shirato S., Slamovits C.H., Spencer D.F., Suzuki S.,
RA Worden A.Z., Zauner S., Barry K., Bell C., Bharti A.K., Crow J.A.,
RA Grimwood J., Kramer R., Lindquist E., Lucas S., Salamov A., McFadden G.I.,
RA Lane C.E., Keeling P.J., Gray M.W., Grigoriev I.V., Archibald J.M.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblProtists:EKX53777}
RP IDENTIFICATION.
RG EnsemblProtists;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; JH992969; EKX53777.1; -; Genomic_DNA.
DR RefSeq; XP_005840757.1; XM_005840700.1.
DR AlphaFoldDB; L1JZL4; -.
DR STRING; 905079.L1JZL4; -.
DR PaxDb; 55529-EKX53777; -.
DR EnsemblProtists; EKX53777; EKX53777; GUITHDRAFT_132829.
DR GeneID; 17310277; -.
DR KEGG; gtt:GUITHDRAFT_132829; -.
DR eggNOG; KOG4362; Eukaryota.
DR HOGENOM; CLU_265430_0_0_1; -.
DR OrthoDB; 318045at2759; -.
DR Proteomes; UP000011087; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd15571; ePHD; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR031099; BRCA1-associated.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13763; BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; 1.
DR PANTHER; PTHR13763:SF6; PHD-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF13771; zf-HC5HC2H; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS51805; EPHD; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000011087};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 192..322
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 944..1186
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT REGION 90..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 406..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 858..895
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1104..1150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..420
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1107..1150
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1255 AA; 140860 MW; BA92668F1F4C738A CRC64;
MTVRLDKSEP RDFILISSDS SDDEKPALNF LLYGLSRSEQ DAYCEGSSSS NLEVLGLPEP
ASHDMLTTAR TASLSEVRCG RIAISDEFDE SGSAAAHDRS HPPRHAPTEA EEEEYHFIQV
KPSNNSQRPR TQQVRKSSRP KKRSVRYAAR EESAEPGAGG GVAAGKKEQK KTEEAKSAQS
PSKGLAASQL DPPTCSFCKK PFKKGAGPEG GGRLLGPIGV KMDVYVHEYC ALFSPQVYFN
REITPDTDVL RNQDLDEKSI RSELRRSNGL RCALCNLSGA SIGCYICSQK SYHFPCAQRA
GLVEWHWWEN HGERIVHCPA HRDPLCEVWW SGDDSFPEQG WFPCAVVDGP IEGHLTVLYS
TPPWGEERLN MRAVRIRFPE SPPVGCTRWQ AFADLFGEEG KETRFGEGEV KGKRVERGHG
GSRQNLSSDR GGRKYDADKN TMESKLNDLL PLAIGSRLGR RNAKRSRTRE DICFREYCAC
ENETPKSLAR KFAVDLKELM ELNVSRFPEL VPSSRFRKNT IVLIPTSPAM SAPLSGELMV
QEYFVEEDET PRSIAKRLKV DVNIVLDFNR SLYPRITPNF KLPRNSVLRV PALYSNDPPS
SPPSMASRFS KGAGGVRSHT SALLHILSKD CLYQIASKLG SDEFLFRFLL SSKQVSRVFD
EMPCIWRHIF RCKFGTEMED QIEKAQTART LVRREQMSSQ KKKTTEMILQ HLATTTTFLT
AKSVASTANL MQLFDSWFKD DTLFELRKRL LLSPRQESDS ERRLGKGKRF QGIIDSNGTI
FNISSSFSSS CSSEHTQMFR DAMEWYRHCQ QLTKQKTPRG EVNLKQYIFF KNQSLADCEK
LFQQHPVEQC MQLIAERTGG EAAEEIEEGK DEGDGGGGGG GGGGGGRRER VRDVSGVQQP
CASLPQTAAS IPTTDYKQAY KYYKEMSLWH IADPYKAGGR RGKEGGREGE TLTGASLSSS
YEKFKMKLQH SCCGTILSRD RREVNKPVSE DCTCIAGLLN EIGFRRGAHL WFIKSRQMNP
GATNERSSFV VGVVTEQRSP GRIFLGCELQ GCGLGFAYQG SSGDIFMTGR ENKTYGVKFM
AGDSVGVLLD CDQKRLSFIV EGNEEKEKEE VGEEEYEEEE EEKEEEEVEE EEEGEEYEEE
EEEKEEEEVP QGIAFDDLPE GSSFWPAVGL HTEGVIISIE HKSAAAFLEK RRKELEELVV
GRRIKKQFPD GVWRNGKIKE KLSEETFMVR FDGGQDLQVR CGVEDGVELL ADEAQ
//
