ID L1KN86_9ACTN Unreviewed; 502 AA.
AC L1KN86;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Putative 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component {ECO:0000313|EMBL:EKX62067.1};
GN ORFNames=STRIP9103_06947 {ECO:0000313|EMBL:EKX62067.1};
OS Streptomyces ipomoeae 91-03.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=698759 {ECO:0000313|EMBL:EKX62067.1, ECO:0000313|Proteomes:UP000010411};
RN [1] {ECO:0000313|EMBL:EKX62067.1, ECO:0000313|Proteomes:UP000010411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91-03 {ECO:0000313|EMBL:EKX62067.1,
RC ECO:0000313|Proteomes:UP000010411};
RA Huguet-Tapia J.C., Durkin A.S., Pettis G.S., Badger J.H.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKX62067.1}.
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DR EMBL; AEJC01000537; EKX62067.1; -; Genomic_DNA.
DR RefSeq; WP_009329907.1; NZ_AEJC01000537.1.
DR AlphaFoldDB; L1KN86; -.
DR PATRIC; fig|698759.3.peg.7241; -.
DR OrthoDB; 9785230at2; -.
DR Proteomes; UP000010411; Unassembled WGS sequence.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.3140.10; 4-hydroxybutyryl-coa dehydratase, domain 1; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR004925; HpaB/PvcC/4-BUDH.
DR InterPro; IPR024719; HpaB/PvcC/4-BUDH_C.
DR InterPro; IPR024674; HpaB/PvcC/4-BUDH_N.
DR PANTHER; PTHR36117; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR36117:SF3; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF03241; HpaB; 1.
DR Pfam; PF11794; HpaB_N; 1.
DR PIRSF; PIRSF000331; HpaA_HpaB; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR000331-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000313|EMBL:EKX62067.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000010411}.
FT DOMAIN 124..186
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT REGION 475..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 189
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
FT BINDING 450..453
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
SQ SEQUENCE 502 AA; 54455 MW; BF06B47682CD8374 CRC64;
MTIRTGAEYL RGLSDGREVW LAGRRVDDVL AEPVLAAAAH TVARLYDQQH DPLLREVLTY
QDGGRRYPLS LAAPRDAQAL RRRGAAFRAT AETTFGLLGR SPDFVNTAVT AFASAAPFFD
KADPRFGRNV TAYHAACLDG DPFLSHATIN PPLSRAHSSH EQDDPDVHLR IVRETSEGVV
VRGAKLIGTL VPVADEIVVF PLPGYRPGDE AYTIAFAIPV ATPGLRIICR EPLVADPTRL
LSTPLAPYEE IDATCVFDDV LVPWDRVFFH GDVDAANRLY DATTARHHTG QHGIVRGAVK
AELLAGVAVA LAEMSGTDTF LHVKEMLGEV LGALELARAG VLAAEADASP SEWGTLTPAI
APVLALRYHF PRMTSRMIEV IQLLGGGSLL STPAEEDLRS ELWPGIERYF RGAHGVSAEQ
RVRLLKLAWD ATGSAFGQRQ MQYERYHSGD PVRLAAAQYT GYDTAPLLRT VQRAMHPAGR
QEADGASGAD PGEARAPGEV RW
//
