ID L1KPK2_9ACTN Unreviewed; 477 AA.
AC L1KPK2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Squalene-associated FAD-dependent desaturase {ECO:0000313|EMBL:EKX62278.1};
GN Name=hpnE {ECO:0000313|EMBL:EKX62278.1};
GN ORFNames=STRIP9103_08535 {ECO:0000313|EMBL:EKX62278.1};
OS Streptomyces ipomoeae 91-03.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=698759 {ECO:0000313|EMBL:EKX62278.1, ECO:0000313|Proteomes:UP000010411};
RN [1] {ECO:0000313|EMBL:EKX62278.1, ECO:0000313|Proteomes:UP000010411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91-03 {ECO:0000313|EMBL:EKX62278.1,
RC ECO:0000313|Proteomes:UP000010411};
RA Huguet-Tapia J.C., Durkin A.S., Pettis G.S., Badger J.H.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKX62278.1}.
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DR EMBL; AEJC01000529; EKX62278.1; -; Genomic_DNA.
DR RefSeq; WP_009329161.1; NZ_AEJC01000529.1.
DR AlphaFoldDB; L1KPK2; -.
DR PATRIC; fig|698759.3.peg.7017; -.
DR OrthoDB; 7849608at2; -.
DR Proteomes; UP000010411; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR001613; Flavin_amine_oxidase.
DR InterPro; IPR017830; SQase_HpnE.
DR NCBIfam; TIGR03467; HpnE; 1.
DR PANTHER; PTHR42923:SF43; BLR3003 PROTEIN; 1.
DR PANTHER; PTHR42923; PROTOPORPHYRINOGEN OXIDASE; 1.
DR Pfam; PF01593; Amino_oxidase; 1.
DR PRINTS; PR00757; AMINEOXDASEF.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000010411}.
FT DOMAIN 30..457
FT /note="Amine oxidase"
FT /evidence="ECO:0000259|Pfam:PF01593"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 477 AA; 50767 MW; 8926DD2931F52E12 CRC64;
MTDGAQSEQP PDADRTGRPR RTAVVVGGGL AGITAALALA DAGVQVTLLE GRPRLGGLAF
SFRRGELTVD NGQHVYLRCC TAYRWFLDRI DGAALAPLQN RLDVPVLDAE GRPGRRLGRL
RRDALPVPLH LGRSLATYTH LSLIERAKVG RAALALKALD LDDPALDERD FGGWLAEHGQ
SARAVEALWD LVGVATLNAV AEDASLGLAA MVFKTGLLSD PGAADIGWAH VPLGELHDRL
ARKALDSAGV RTGLRTRVTS VSPCGDGRWT VQVPGESLDA DAVVLAVPQR ETHDLLPAGA
LDAPERLLRI GTAPILNVHV VYDRKVLKRP FFAALGSPVQ WVFDRTGASG LREGQYLALS
QSAAQDEIDA PVAALRARYL PELERLLPGV RGAAVKDFFV TRERTATFAP TPGVGRLRPG
ARTKAPGLYL AGAWTATGWP ATMESAVRSG VSAADAALAT LGRPRDHLFA HEHEEAA
//
