ID L1KZF1_9ACTN Unreviewed; 1092 AA.
AC L1KZF1;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Putative linear gramicidin synthetase LgrD {ECO:0000313|EMBL:EKX66017.1};
GN ORFNames=STRIP9103_06875 {ECO:0000313|EMBL:EKX66017.1};
OS Streptomyces ipomoeae 91-03.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=698759 {ECO:0000313|EMBL:EKX66017.1, ECO:0000313|Proteomes:UP000010411};
RN [1] {ECO:0000313|EMBL:EKX66017.1, ECO:0000313|Proteomes:UP000010411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91-03 {ECO:0000313|EMBL:EKX66017.1,
RC ECO:0000313|Proteomes:UP000010411};
RA Huguet-Tapia J.C., Durkin A.S., Pettis G.S., Badger J.H.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKX66017.1}.
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DR EMBL; AEJC01000250; EKX66017.1; -; Genomic_DNA.
DR AlphaFoldDB; L1KZF1; -.
DR PATRIC; fig|698759.3.peg.3357; -.
DR OrthoDB; 2472181at2; -.
DR Proteomes; UP000010411; Unassembled WGS sequence.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd05235; SDR_e1; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.820.10; Structural Genomics, Unknown Function 30-nov-00 1gh9 Mol_id; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020459; AMP-binding.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR013120; Far_NAD-bd.
DR InterPro; IPR005153; MbtH-like_dom.
DR InterPro; IPR038020; MbtH-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR010080; Thioester_reductase-like_dom.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR NCBIfam; TIGR01746; Thioester-redct; 1.
DR PANTHER; PTHR44845:SF6; BETA-ALANINE-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR44845; CARRIER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF03621; MbtH; 1.
DR Pfam; PF07993; NAD_binding_4; 1.
DR Pfam; PF00550; PP-binding; 1.
DR PRINTS; PR00154; AMPBINDING.
DR SMART; SM00923; MbtH; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF160582; MbtH-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Reference proteome {ECO:0000313|Proteomes:UP000010411}.
FT DOMAIN 594..674
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1092 AA; 117965 MW; 39B6BD015F6E0A42 CRC64;
MTEPDDPSAE SAAPCVVLRN DEEQYAIWPA ERRIPAGWRP IGAPASAARC GRLVDRLWTD
MRPASARAKG RLAGSAPSTV PDLVRERARR EPSALAVLSD EGRLSYAELT GRAERLAHEL
RESGVDAESV VGVCLDRGPE LVVALLAVLN SGGAFLPLDP ATPRQRTVAL VGETGSRLIV
SSREHALTFA ECEARIVHVG SARGAVTRTP PAKPPRARGP RPDDLAYVIY TSGSTGPPKG
VMITHRALSH SLTAVARAYE LAPGDRVLHS AALGFDTSLE QIFATLISGA TLVLAGTRMW
APTDLLHRLP EHGITVADLT PAYWHRLLSI ADRGESLASL RLAIVGGEIV GVKDCRALLR
RIPGARLVNA YGLTETAITS MLCELNEEVL AAPDTAVAPV GRPLAGSHVH LLDAELRPVP
PGERGEIYIG GPVLARGIWR QPALTAQQFT ADPHGSAPDR MYRTGDLGRR RSDGNLEVLG
RVDDQMKIRG FRVDPAEIEA ALVSRPEVGE AMVVARLRDN GDRDIVAYYT PTASSAGDDT
VLPTRLRSAL AEVLPGYMIP AAFHTVERLP VTPGGKLDRR AVPELKATAT TGGTDDRPVP
QGMAQLWSQI LDVDYVRPHD DFFELGGNSL LAMEMLARTR VVFGIGVTQI RDLTRSLLRY
PTLAAFAESV RQARAGTLAH PAGGSIDFAA EADRSVPVAG RDAPAPDPRH PGDVLLTGAT
GFCGAYMIDE LLRRTTGRIL CLVRASDDQH GMERIRASHQ RHVRSVLSST RVQPVVGDLG
KPGLGLSPSR FEELGSIIDA VYHFGGQVNF IYPYHELRAA NVDGTYEIIR LAAGRSVPVH
FTSSMAVLAG FGRAGVREVT ESTPLRFPEY LSVGYVETKW VAEALLRKAS DAGLPVAVHR
LMDITGSSGT GVMNTSSEMA ALIDFIARTG LCPDVRLPLD FLPADHLARA IGHISTHRPA
HGEVYHLTNP RPTLLSSLAE RLRRRGCPVQ EIPYGEWTAA LVKHAAGHPT DAITPFVPLF
VDRCHRADIT VSEMYFLDVF PEFTADNGER ALKDAGIDVP PVDAEMLDRY IDFLRQPDHL
QPVERHEHGA AQ
//
