ID L1L1B3_9ACTN Unreviewed; 720 AA.
AC L1L1B3;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
GN ORFNames=STRIP9103_08829 {ECO:0000313|EMBL:EKX66589.1};
OS Streptomyces ipomoeae 91-03.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=698759 {ECO:0000313|EMBL:EKX66589.1, ECO:0000313|Proteomes:UP000010411};
RN [1] {ECO:0000313|EMBL:EKX66589.1, ECO:0000313|Proteomes:UP000010411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91-03 {ECO:0000313|EMBL:EKX66589.1,
RC ECO:0000313|Proteomes:UP000010411};
RA Huguet-Tapia J.C., Durkin A.S., Pettis G.S., Badger J.H.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 42 family.
CC {ECO:0000256|ARBA:ARBA00005940}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKX66589.1}.
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DR EMBL; AEJC01000209; EKX66589.1; -; Genomic_DNA.
DR RefSeq; WP_009310155.1; NZ_AEJC01000209.1.
DR AlphaFoldDB; L1L1B3; -.
DR PATRIC; fig|698759.3.peg.2844; -.
DR OrthoDB; 9800974at2; -.
DR Proteomes; UP000010411; Unassembled WGS sequence.
DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd03143; A4_beta-galactosidase_middle_domain; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR013738; Beta_galactosidase_Trimer.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR003476; Glyco_hydro_42.
DR InterPro; IPR013529; Glyco_hydro_42_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR36447; BETA-GALACTOSIDASE GANA; 1.
DR PANTHER; PTHR36447:SF2; BETA-GALACTOSIDASE YESZ; 1.
DR Pfam; PF02449; Glyco_hydro_42; 1.
DR Pfam; PF08532; Glyco_hydro_42M; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000010411}.
FT DOMAIN 27..400
FT /note="Glycoside hydrolase family 42 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02449"
FT DOMAIN 483..635
FT /note="Beta-galactosidase trimerisation"
FT /evidence="ECO:0000259|Pfam:PF08532"
SQ SEQUENCE 720 AA; 80597 MW; 9A3F4AAE4124597D CRC64;
MAALPARVLF GAAYYHEYRP AHDTARPDER LKTDLDLMAD AQVTVIRVGE SVWSTWEPTS
GVFDLDWLQP VLDGAHERGI SVVLGTPTYA VPPWLARQYP EITGEQRTGE RIGWGARQEV
DFTHPAFRFH AERVIRRIVA RYADHPAVIG FQVDNEPGLH LFHNHGVFQR FVDHLREKYG
DVETLNREWG LVYWSHRLST WADLWTPDGN AQPQYDVAWR EFQARQVTEF IGWQADIVRE
YARPEQFVTT CISYTRQGVE DDELSHRLDI ASGNPYYDMQ DGLLLPDPTP DDHEQIWKTT
GVWALYQTAD WMFSSRQEPF LVTETNAGSI GFPWDNRPAY DGQWRQAAWA LVGRGARMIE
YWHWNTLHFG AETYWGGVLP HTGRPGRTYA ELARLGAEFD TAGSLVAGLE PDADITMVYS
TPSKWLMQKY PPLAKPSGEP DPAAYHRFFD PFYRGAFDSG RQVRIVHARQ LHDPRGEREG
LAPQEAVRRH PVLVVPALYI ADDATLDWFA AYAEAGGHLV LGPRTGYADH EARARTEPAP
GRLVEAAGVQ YDEFGNLARE IPVRPTPGSP LRLPEGAAAT RWADGLTVDD ADVLATYEHP
HFGRWPALTT RRHGAGRVTC VGTVPDRGLG RALAEWLTPT ARHGWRDLPA TVTATTGTAP
DGRRVHIVHN WSWEPTSAPA PVDLTDALNG TPVPAGTALD LGAWDVRVLV SGGSAPDHNS
//
