ID L1L2B7_9ACTN Unreviewed; 422 AA.
AC L1L2B7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Aldehyde dehydrogenase (NAD) family protein {ECO:0000313|EMBL:EKX66753.1};
GN ORFNames=STRIP9103_00912 {ECO:0000313|EMBL:EKX66753.1};
OS Streptomyces ipomoeae 91-03.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=698759 {ECO:0000313|EMBL:EKX66753.1, ECO:0000313|Proteomes:UP000010411};
RN [1] {ECO:0000313|EMBL:EKX66753.1, ECO:0000313|Proteomes:UP000010411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91-03 {ECO:0000313|EMBL:EKX66753.1,
RC ECO:0000313|Proteomes:UP000010411};
RA Huguet-Tapia J.C., Durkin A.S., Pettis G.S., Badger J.H.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKX66753.1}.
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DR EMBL; AEJC01000194; EKX66753.1; -; Genomic_DNA.
DR AlphaFoldDB; L1L2B7; -.
DR PATRIC; fig|698759.3.peg.2666; -.
DR Proteomes; UP000010411; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR43111; ALDEHYDE DEHYDROGENASE B-RELATED; 1.
DR PANTHER; PTHR43111:SF1; ALDEHYDE DEHYDROGENASE B-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000010411}.
FT DOMAIN 9..410
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 178
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 422 AA; 46225 MW; 5342A5B754FF127B CRC64;
MEDRRSDAAN LEKLAVAESW ENGKPVRETL AADIPLAIDH FRYFAGAIRA QEGSLAELDD
DTVAYHFHEP LGVVAQIIPW NFPILMATWK LAPALAAGNA VVLKPAEQTP ASIHVWLSLV
SDLLPPGVVN IVNGFGVEAG KPLASSPRVA KVAFTGETTT GRLIMQYASE NITPVTLELG
GKSPNIFFDD VWSANDDFRD KALEGFTMFA LNQGEVCTCP SRALVQRGHY AEFMEAAVAR
TEQIKTGHPL DTDTMIGAQA SNDQLEKILS YLDIGRQEGA KVLTGGERIE HDGELKGGYY
VQPTIFEGDN RMRIFQEEIF GPVVSVTSFN DFDDAIKIAN DTLYGLGAGV WTRDANTAYR
AGRSIQAGRV WTNCYHAYPA HAAFGGYKGS GIGRETHKMM LDHYQQTKNI LCSYSPQKLG
FF
//
