ID L1L3Y7_9ACTN Unreviewed; 324 AA.
AC L1L3Y7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Daunorubicin resistance ABC transporter, ATP-binding protein {ECO:0000313|EMBL:EKX67298.1};
GN ORFNames=STRIP9103_04199 {ECO:0000313|EMBL:EKX67298.1};
OS Streptomyces ipomoeae 91-03.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=698759 {ECO:0000313|EMBL:EKX67298.1, ECO:0000313|Proteomes:UP000010411};
RN [1] {ECO:0000313|EMBL:EKX67298.1, ECO:0000313|Proteomes:UP000010411}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91-03 {ECO:0000313|EMBL:EKX67298.1,
RC ECO:0000313|Proteomes:UP000010411};
RA Huguet-Tapia J.C., Durkin A.S., Pettis G.S., Badger J.H.;
RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKX67298.1}.
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DR EMBL; AEJC01000159; EKX67298.1; -; Genomic_DNA.
DR RefSeq; WP_009307329.1; NZ_AEJC01000159.1.
DR AlphaFoldDB; L1L3Y7; -.
DR PATRIC; fig|698759.3.peg.2143; -.
DR OrthoDB; 9804819at2; -.
DR Proteomes; UP000010411; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043215; P:daunorubicin transport; IEA:InterPro.
DR GO; GO:1900753; P:doxorubicin transport; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR005894; DrrA.
DR InterPro; IPR025302; DUF4162.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01188; drrA; 1.
DR PANTHER; PTHR42711; ABC TRANSPORTER ATP-BINDING PROTEIN; 1.
DR PANTHER; PTHR42711:SF18; DOXORUBICIN RESISTANCE ATP-BINDING PROTEIN DRRA; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF13732; DUF4162; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:EKX67298.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000010411};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 11..241
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 324 AA; 34854 MW; 474A6871A3A262BE CRC64;
MSDGTGDGYA VRAEGLEKRY GEKRALDGFD LTVREGTVHG LLGPNGAGKT TAVRILSTLV
RLDGGRATVA GLDVARHPRG VRARIGLTGQ YAAVDEVLTG RQNLEMFGRL FHLGGKRAKR
RAVELLDQFD LTDAADKGVG GYSGSMRRRL DLAASMILAP AVLFLDEPTT GLDPRSRGEV
WESVRALVAS GTTVLLTTQY LEEADRLASR ITVIDQGRAI ADDTPDGLKN TVGGDRVEVV
VTERADIPRA VKIVARVADG EPESDDTELR VHAPVADRVT ALTEVARTLQ DEGIPVEDIG
LRRPSLDDVF LRLTGHRTEK ETAA
//
