ID L1LBT7_THEEQ Unreviewed; 842 AA.
AC L1LBT7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=NFACT RNA-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BEWA_012840 {ECO:0000313|EMBL:EKX72725.1};
OS Theileria equi strain WA.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Piroplasmida;
OC Theileriidae; Theileria.
OX NCBI_TaxID=1537102 {ECO:0000313|EMBL:EKX72725.1, ECO:0000313|Proteomes:UP000031512};
RN [1] {ECO:0000313|EMBL:EKX72725.1, ECO:0000313|Proteomes:UP000031512}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WA {ECO:0000313|EMBL:EKX72725.1,
RC ECO:0000313|Proteomes:UP000031512};
RX PubMed=23137308; DOI=10.1186/1471-2164-13-603;
RA Kappmeyer L.S., Thiagarajan M., Herndon D.R., Ramsay J.D., Caler E.,
RA Djikeng A., Gillespie J.J., Lau A.O., Roalson E.H., Silva J.C., Silva M.G.,
RA Suarez C.E., Ueti M.W., Nene V.M., Mealey R.H., Knowles D.P., Brayton K.A.;
RT "Comparative genomic analysis and phylogenetic position of Theileria
RT equi.";
RL BMC Genomics 13:603-603(2012).
CC -!- SIMILARITY: Belongs to the NEMF family.
CC {ECO:0000256|ARBA:ARBA00008318}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKX72725.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ACOU01000004; EKX72725.1; -; Genomic_DNA.
DR AlphaFoldDB; L1LBT7; -.
DR STRING; 1537102.L1LBT7; -.
DR EnsemblProtists; EKX72725; EKX72725; BEWA_012840.
DR VEuPathDB; PiroplasmaDB:BEWA_012840; -.
DR eggNOG; KOG2030; Eukaryota.
DR OrthoDB; 129892at2759; -.
DR Proteomes; UP000031512; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0072344; P:rescue of stalled ribosome; IEA:UniProt.
DR InterPro; IPR021846; NFACT-C.
DR InterPro; IPR008532; NFACT_RNA-bd.
DR PANTHER; PTHR15239; NUCLEAR EXPORT MEDIATOR FACTOR NEMF; 1.
DR PANTHER; PTHR15239:SF6; RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF; 1.
DR Pfam; PF11923; NFACT-C; 1.
DR Pfam; PF05670; NFACT-R_1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000031512}.
FT DOMAIN 367..478
FT /note="NFACT RNA-binding"
FT /evidence="ECO:0000259|Pfam:PF05670"
FT DOMAIN 751..818
FT /note="NFACT protein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11923"
FT REGION 514..594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 716..742
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..539
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 540..577
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 842 AA; 95997 MW; D2A38A41D8BDE7FC CRC64;
MITSTLFQNY LLIRHYMKQP PSPNNHLYVV HFFYPLIFTS IGPQNTGDHF FKVGTTYLFD
EEYHSWCKKL SKDVISGILD TPKPLSDIVK QIYPSVHASL VEFILKKSGE SPTREFCSQD
VDLAMQFIEA LRKEVLRLTS SDSTIGGYLF KAQNGEYDDF SPFEIKADGE FFADYNEALD
AFFTKSEIKK EEKKVVDKKP TKLKKIKLDQ DRREGKLIDE IKVLQTDIEI LQENIDLVDK
CLNLIRTLIA TGASWKDIQD QIEIQKTLKH PIAQRIAKID IPNQIVTFAG DPNDKSGPEI
EYGLSCHQNL EKMYSKKKKL ESKLERTKIG REFALKKVNK EKEKEQTQVK GPTHKITTLR
KRFWFEKFYW FITSDGYLVL GGRDALQNEI LVKKYLTKGD LYFHADIHGA SSCILKNPGQ
VAEIPQTSID QGGCFAVCHS NAWNQKFMVP SWWVYHHQVS KTPPTGEFVP QGSFVIRGKK
NYIQPQKLEM GLTVVFHIGN VDEDEDNAAV EANIEEEQND EPKDDFGGDE SKLTESDEVD
ENVTSEESES GDKESEDDKS DESEEAVNDS RDSEDDDDED EKKMHKPSVR INTESVTITE
IECTVKRSTK QRKATGYPKA LEVDLESIKE QLGALNLLAE PKDGHVNITE PGKLFHTEEA
SRKIRERIPT GVKKKEPMSK AARNKLAKMK KKYGSDDEET QELRRLLTGS TKLKVIKQAE
EEPAVQPSAP RPRTQPSQDT LKTIDDKELE RYMKQFNRLC KDPKEDDIIL NAIPMCAPFS
ALREFKTRIK LVPGNTKKGA IASQALHQFA KSDEKRANYI KLITSDQLIL TMIGNCKVPT
SK
//
