ID   L1M812_9CORY            Unreviewed;       202 AA.
AC   L1M812;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=dTMP kinase {ECO:0000313|EMBL:EKX87373.1};
GN   ORFNames=HMPREF9997_02699 {ECO:0000313|EMBL:EKX87373.1};
OS   Corynebacterium durum F0235.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC   Corynebacteriaceae; Corynebacterium.
OX   NCBI_TaxID=1035195 {ECO:0000313|EMBL:EKX87373.1, ECO:0000313|Proteomes:UP000010445};
RN   [1] {ECO:0000313|EMBL:EKX87373.1, ECO:0000313|Proteomes:UP000010445}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0235 {ECO:0000313|EMBL:EKX87373.1,
RC   ECO:0000313|Proteomes:UP000010445};
RA   Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA   Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA   Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA   Pepin K.H., Bhonagiri V., Zhang X., Suruliraj S., Warren W., Mitreva M.,
RA   Mardis E.R., Wilson R.K.;
RL   Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + dTMP = ADP + dTDP; Xref=Rhea:RHEA:13517,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58369, ChEBI:CHEBI:63528,
CC         ChEBI:CHEBI:456216; EC=2.7.4.9;
CC         Evidence={ECO:0000256|ARBA:ARBA00001008};
CC   -!- SIMILARITY: Belongs to the thymidylate kinase family.
CC       {ECO:0000256|ARBA:ARBA00009776}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKX87373.1}.
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DR   EMBL; AMEM01000044; EKX87373.1; -; Genomic_DNA.
DR   RefSeq; WP_006062502.1; NZ_KB290826.1.
DR   AlphaFoldDB; L1M812; -.
DR   STRING; 1035195.HMPREF9997_02699; -.
DR   GeneID; 84896255; -.
DR   PATRIC; fig|1035195.3.peg.2415; -.
DR   eggNOG; COG0125; Bacteria.
DR   HOGENOM; CLU_049131_1_0_11; -.
DR   OrthoDB; 9774907at2; -.
DR   Proteomes; UP000010445; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR039430; Thymidylate_kin-like_dom.
DR   PANTHER; PTHR10344; THYMIDYLATE KINASE; 1.
DR   PANTHER; PTHR10344:SF4; THYMIDYLATE KINASE; 1.
DR   Pfam; PF02223; Thymidylate_kin; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000313|EMBL:EKX87373.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010445};
KW   Transferase {ECO:0000313|EMBL:EKX87373.1}.
FT   DOMAIN          5..180
FT                   /note="Thymidylate kinase-like"
FT                   /evidence="ECO:0000259|Pfam:PF02223"
SQ   SEQUENCE   202 AA;  22327 MW;  A7025F946210A4FD CRC64;
     MIISIEGIDG AGKNTLVRAL TSRIDAATLT FPRYDTSIHA QLAARALHGQ MGDLVDSAHG
     MATLFALDRY GAREVLDRYA DSDEVLLLDR YVASNAAYTA ARLKDDAAFD WVYDLEFGQL
     GLPVPHLQVL LETSVDEASI RAQKREAYDA TRTRDAYEKD GELQDRTFAA YQQLAAKQWA
     SPWLTSSDAD DVSEHIIQVI SS
//