ID L1MHX8_9CORY Unreviewed; 397 AA.
AC L1MHX8;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Thiaminepyrophosphokinase, catalytic domain protein {ECO:0000313|EMBL:EKX90554.1};
GN ORFNames=HMPREF9997_01049 {ECO:0000313|EMBL:EKX90554.1};
OS Corynebacterium durum F0235.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=1035195 {ECO:0000313|EMBL:EKX90554.1, ECO:0000313|Proteomes:UP000010445};
RN [1] {ECO:0000313|EMBL:EKX90554.1, ECO:0000313|Proteomes:UP000010445}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0235 {ECO:0000313|EMBL:EKX90554.1,
RC ECO:0000313|Proteomes:UP000010445};
RA Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA Pepin K.H., Bhonagiri V., Zhang X., Suruliraj S., Warren W., Mitreva M.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKX90554.1}.
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DR EMBL; AMEM01000017; EKX90554.1; -; Genomic_DNA.
DR RefSeq; WP_006063287.1; NZ_KB290831.1.
DR AlphaFoldDB; L1MHX8; -.
DR STRING; 1035195.HMPREF9997_01049; -.
DR PATRIC; fig|1035195.3.peg.934; -.
DR eggNOG; COG4825; Bacteria.
DR HOGENOM; CLU_046690_0_0_11; -.
DR OrthoDB; 5169996at2; -.
DR Proteomes; UP000010445; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004788; F:thiamine diphosphokinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009229; P:thiamine diphosphate biosynthetic process; IEA:InterPro.
DR InterPro; IPR047795; Put_SteA-like.
DR InterPro; IPR022215; SteA-like_C.
DR InterPro; IPR036759; TPK_catalytic_sf.
DR NCBIfam; NF040608; division_SteA; 1.
DR Pfam; PF12555; SteA-like_C; 1.
DR SUPFAM; SSF63999; Thiamin pyrophosphokinase, catalytic domain; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EKX90554.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000010445};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 351..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 337..388
FT /note="SteA-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12555"
SQ SEQUENCE 397 AA; 42097 MW; 2F13CC9A82E729A9 CRC64;
MSAMSLFSRN ADLPGLQGVV RDCSATGKGF KRLAPGDIAV VDAPDIDRSL AQRLIDAKVA
VVINTSQFTT GSVPNYGPQM MLDAGMLLIE GVGSDVWSSV KDGKKGRVTD EGKLFFGERL
AASGTVLEQE WAESAFSDAQ QSLMDDMEAF FGNTIQFIHS ETPLLIDGIG IPSTGIDFKD
RKVLIVGPGY EHRKQVKELR NFIREYDPVL VGVDEAADTL VDLGYKPDLI VGNPAGIGAE
ALRSGAKVVL PADPDGHAIG LERIQDLGVG AMTFPAASDS ATDLALLLAD YHGASMIVNA
GSPLDLGMIF NEEPEATPSA LLTRAKVGAK LVDARSVIEL YTIRSAGNLG WLWVIFGLLV
AVGVIVAIAG TAGDGSFADN LVNTWNNMTG TVRGWFR
//
