ID   L1NBF8_9BACT            Unreviewed;       938 AA.
AC   L1NBF8;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Peptidase, M16 family {ECO:0000313|EMBL:EKY00542.1};
GN   ORFNames=HMPREF9151_01222 {ECO:0000313|EMBL:EKY00542.1};
OS   Hoylesella saccharolytica F0055.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Hoylesella.
OX   NCBI_TaxID=1127699 {ECO:0000313|EMBL:EKY00542.1, ECO:0000313|Proteomes:UP000010433};
RN   [1] {ECO:0000313|EMBL:EKY00542.1, ECO:0000313|Proteomes:UP000010433}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0055 {ECO:0000313|EMBL:EKY00542.1,
RC   ECO:0000313|Proteomes:UP000010433};
RA   Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA   Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA   Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA   Pepin K.H., Bhonagiri V., Zhang X., Suruliraj S., Warren W., Mitreva M.,
RA   Mardis E.R., Wilson R.K.;
RL   Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKY00542.1}.
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DR   EMBL; AMEP01000085; EKY00542.1; -; Genomic_DNA.
DR   RefSeq; WP_009162437.1; NZ_KB290995.1.
DR   AlphaFoldDB; L1NBF8; -.
DR   STRING; 1127699.HMPREF9151_01222; -.
DR   PATRIC; fig|1127699.3.peg.1131; -.
DR   HOGENOM; CLU_008156_0_0_10; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000010433; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR43690; NARDILYSIN; 1.
DR   PANTHER; PTHR43690:SF34; ZINC PROTEASE PQQL-LIKE; 1.
DR   Pfam; PF00675; Peptidase_M16; 1.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 3.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW   Protease {ECO:0000256|ARBA:ARBA00022670};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010433};
KW   Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..938
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003954226"
FT   DOMAIN          50..168
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          206..390
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   DOMAIN          713..869
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   938 AA;  105967 MW;  08753422F3B68B65 CRC64;
     MRIKNWFLLV LLSVAGTVQA QMLMTKLPVD SAVRIGKLKN GLTYYIRYNN WPEHRANFYI
     AQKVGSIQEE ENQRGLAHFL EHMCFNGTKH FPGDALLRYC ESLGVKFGVD LNAYTSIDQT
     VYNIDNVPTA RQSALDSCLL ILRDWAGSLT LDPKEIDQER GVIHEEWRLR TSARSRMFER
     NLPKLYPGSK YGVRYPIGLM SVVDNFKYKE LRNYYEKWYH PNNQGIIVVG DVDVDHVEAE
     IKRLFGDLKN PLNALPVVDE KVPDNHAPIV IIDKDKEERS SIVQLMMKHE ATPDSVKGNL
     KYLIYLYIKE VGIGLLNERL NEVAQKPDCP FVGAGTSDGN YIFAKTKDAF TIAAVPKDIS
     LTAAALKAVY EEALRAAEFG FTETEYNRSK INALSSLDKM YSNRDKRFTE QFASEYKDHF
     LSNEPIPSLE YSYQMLKQIV PNVPIEYVNE VFKSLVSKSD TNLVIINFNP EKEGSVYPTE
     TQLLTAVKEA RTEKLAPYVD NVKDEPLMSK LPKPGKIKSE KRNEKFDFTE IKLSNGVTVL
     LKKTDFKKDE VALNGNGGGG SSFYGEKDFI NLEVFDNVIN ISGLGNFSNT ELTKAMAGKI
     ATVSLTMGDK RMQVSGSSTP KDMEAMLQLM YLHFTKIAKD QKSFDTMIES LKINLKNRSA
     SPDIAYQDSV TATMYGHNKR VKPMELSDLP AINYDRILQM VAERTANANG WRFTIIGNYD
     ENTIRPLICR YLGSLPSKGK NVKGKRVLNL QKGIVNNDFT RKMETPKANA TMVWFNEDMP
     YTTETAIKAN IAGQILSMVY LKKIREEASA AYSCGAAGSA TIDDDYHNVT IYAYCPMKPE
     KSTEALQIMH DEMQNLATTC DASMLAKVKE YMLKEADDAV KTNGYWVNVI GMFYRYGIDS
     HTDYKALVAA QTPESISSFV KDFLKAGNRI QVTMMPEK
//