ID L1NL84_9NEIS Unreviewed; 229 AA.
AC L1NL84;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 08-NOV-2023, entry version 35.
DE SubName: Full=Sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family {ECO:0000313|EMBL:EKY04133.1};
GN ORFNames=HMPREF9120_02430 {ECO:0000313|EMBL:EKY04133.1};
OS Neisseria sp. oral taxon 020 str. F0370.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=1127694 {ECO:0000313|EMBL:EKY04133.1, ECO:0000313|Proteomes:UP000010457};
RN [1] {ECO:0000313|EMBL:EKY04133.1, ECO:0000313|Proteomes:UP000010457}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0370 {ECO:0000313|EMBL:EKY04133.1,
RC ECO:0000313|Proteomes:UP000010457};
RA Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA Pepin K.H., Bhonagiri V., Zhang X., Suruliraj S., Warren W., Mitreva M.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKY04133.1}.
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DR EMBL; AMER01000185; EKY04133.1; -; Genomic_DNA.
DR AlphaFoldDB; L1NL84; -.
DR STRING; 1127694.HMPREF9120_02430; -.
DR PATRIC; fig|1127694.3.peg.2247; -.
DR HOGENOM; CLU_081811_2_3_4; -.
DR Proteomes; UP000010457; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR CDD; cd03360; LbH_AT_putative; 1.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR020019; AcTrfase_PglD-like.
DR InterPro; IPR041561; PglD_N.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR NCBIfam; TIGR03570; NeuD_NnaD; 1.
DR PANTHER; PTHR43300; ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR43300:SF7; UDP-N-ACETYLBACILLOSAMINE N-ACETYLTRANSFERASE; 1.
DR Pfam; PF17836; PglD_N; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000313|EMBL:EKY04133.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010457};
KW Transferase {ECO:0000313|EMBL:EKY04133.1}.
FT DOMAIN 24..102
FT /note="PglD N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17836"
FT ACT_SITE 158
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
FT BINDING 91
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT BINDING 167
FT /ligand="acetyl-CoA"
FT /ligand_id="ChEBI:CHEBI:57288"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT BINDING 188
FT /ligand="acetyl-CoA"
FT /ligand_id="ChEBI:CHEBI:57288"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT SITE 159
FT /note="Increases basicity of active site His"
FT /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
SQ SEQUENCE 229 AA; 22800 MW; BDB7B5D7FC31D59E CRC64;
MTAVGGTAFR PDRQTEKRFM DSKNLVIIGA GGHGKVLAAT ALAAAQWARI VFLDDARTAG
GSVVGLPVLG GTELLGSRVA PDAYQAAVAV GDNAARRRLF GRLKTLGFAL PDIVHPSAVV
APFAQLGGGC AVFAQAVVQP GSVMGEGCIV NTAATIDHDC TLGGFVHISP GAHLAGGTAV
GEGSWIGIGA CTRQQVRIGS GVTVGAGAAV VGDVADGLTV VGVPARALR
//
