ID L1QEC4_9CLOT Unreviewed; 702 AA.
AC L1QEC4;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Nitrate reductase, catalytic subunit {ECO:0000313|EMBL:EKY26339.1};
GN ORFNames=HMPREF0216_01980 {ECO:0000313|EMBL:EKY26339.1};
OS Clostridium celatum DSM 1785.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=545697 {ECO:0000313|EMBL:EKY26339.1, ECO:0000313|Proteomes:UP000010420};
RN [1] {ECO:0000313|EMBL:EKY26339.1, ECO:0000313|Proteomes:UP000010420}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1785 {ECO:0000313|EMBL:EKY26339.1,
RC ECO:0000313|Proteomes:UP000010420};
RA Weinstock G., Sodergren E., Lobos E.A., Fulton L., Fulton R., Courtney L.,
RA Fronick C., O'Laughlin M., Godfrey J., Wilson R.M., Miner T., Farmer C.,
RA Delehaunty K., Cordes M., Minx P., Tomlinson C., Chen J., Wollam A.,
RA Pepin K.H., Bhonagiri V., Zhang X., Suruliraj S., Warren W., Mitreva M.,
RA Mardis E.R., Wilson R.K.;
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- PATHWAY: Nitrogen metabolism. {ECO:0000256|ARBA:ARBA00004909}.
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. NasA/NapA/NarB subfamily.
CC {ECO:0000256|ARBA:ARBA00008747}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKY26339.1}.
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DR EMBL; AMEZ01000057; EKY26339.1; -; Genomic_DNA.
DR AlphaFoldDB; L1QEC4; -.
DR STRING; 545697.HMPREF0216_01980; -.
DR PATRIC; fig|545697.3.peg.1947; -.
DR eggNOG; COG0243; Bacteria.
DR HOGENOM; CLU_000422_13_4_9; -.
DR Proteomes; UP000010420; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd00508; MopB_CT_Fdh-Nap-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR PANTHER; PTHR43105:SF9; NITRATE REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15190)-RELATED; 1.
DR PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR PIRSF; PIRSF000144; CbbBc; 2.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000010420}.
FT DOMAIN 8..64
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 702 AA; 78750 MW; ED10E27128EF132D CRC64;
MKWRWKVMKK IQSTCNLCAL ACNVDFHVEN DKIVKVSPTV DYPVNKGFCC IKGLNLDKQQ
TKIKARKSPL LRDENGEMKE ISWEEGIKTF AEKMTAIQEK YGKESVAFIS TGQMPTEDMA
LLGHVGRNHM GINGDGNTRL CMATSVVAHK QSFGFDAPPY TLNDAELSDT IILIGGNPVI
AHPVFWGRIK ANKEAKIITI DPRKSETAMN SDIWIDIKPK ADLVLMYTLA NVLIEKGYID
VNYIENHTEG YEDFKNHVAK FTLENVEAET GISAERVIEL AEIIHAGERV SFWWTMGINQ
GYQAVRTAQS IINLALITGN MGRPGTGANS LTGQCNAMGS RAFSNTAGLF GGGDFDNPVR
RKAVAEAIGV DESYLATKPT IPYNAIIEKA IAGEIKGLWV ICTNPRHSWA NNEEFEKCVK
NLDFFVVQDI YEDTDSAKLA DLYLPSVPAI KKEGVLINTE RRLSKVNPVI SKEEGELSDF
EIFYKIGQEL GMGDNLKGWE TPRSVFELLK KCSKGMPCDI TGVTYEMLEG PNMEGSRGVQ
WPFRAGETLV DDERRLYEDG NYYTPSKKAK FHFEDIAENP TQASEEFPYI FNSGRGTVGQ
WHTQVRSREI EESERIYSKE SYAFMHPELA KELNIVENER VSIASQNGVT KDFTIKISDH
VKKDHLYAPI HYIETNALTP SVYDPYSKEP SFKTVAVNVI KK
//
