ID L2F881_9GAMM Unreviewed; 387 AA.
AC L2F881;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=MOMA_08921 {ECO:0000313|EMBL:ELA08668.1};
OS Moraxella macacae 0408225.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Moraxella.
OX NCBI_TaxID=1230338 {ECO:0000313|EMBL:ELA08668.1, ECO:0000313|Proteomes:UP000023795};
RN [1] {ECO:0000313|EMBL:ELA08668.1, ECO:0000313|Proteomes:UP000023795}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0408225 {ECO:0000313|EMBL:ELA08668.1,
RC ECO:0000313|Proteomes:UP000023795};
RX PubMed=23409273;
RA Ladner J.T., Whitehouse C.A., Koroleva G.I., Palacios G.F.;
RT "Genome Sequence of Moraxella macacae 0408225, a Novel Bacterial Species
RT Isolated from a Cynomolgus Macaque with Epistaxis.";
RL Genome Announc. 1:E00188-12(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ELA08668.1}.
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DR EMBL; ANIN01000002; ELA08668.1; -; Genomic_DNA.
DR AlphaFoldDB; L2F881; -.
DR STRING; 1230338.MOMA_08921; -.
DR PATRIC; fig|1230338.3.peg.1914; -.
DR eggNOG; COG1024; Bacteria.
DR Proteomes; UP000023795; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000023795}.
FT DOMAIN 27..375
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 387 AA; 43080 MW; 404E093DE9995853 CRC64;
MNETYQTVKT DFVLFDTLPT DDGNLLGMIT LNAPKALNAL DLTMCQQILQ QLQIWQNEAK
IVAIFLQGTG EKAFCAGGNI RKIYDSMIQK PAVSEPCPIN LSTLDYAEAF FVNEYRLNRY
MASYTKPIIA WASGIVMGGG LGLVATCSHR IVTETTRFAM PEINIGLFPD ATGSWFLQKM
PAQTGLFFGL TGANGNAGDA LLANLAEFSV RSEQKSAVLQ ALQKADWQKT CAKFVVSQAL
SQLHTTEHLP DSHVVKHWQT LQKIVNAGDM LAIDDLLRNS AFIAKYCQDE WLAQAIDTYQ
HGCPVSASLT FALFHRLKTL SLPKILQIEL NTAIHCCHFP DFREGVRALL VDKDKNPMWH
KTLATITPEY INTHFDDVYQ GDELLVL
//
