ID   L2FF32_COLFN            Unreviewed;      1160 AA.
AC   L2FF32;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   28-JUN-2023, entry version 44.
DE   SubName: Full=Nonsense-mediated mrna decay factor {ECO:0000313|EMBL:ELA24666.1};
GN   ORFNames=CGGC5_2056 {ECO:0000313|EMBL:ELA24666.1};
OS   Colletotrichum fructicola (strain Nara gc5) (Anthracnose fungus)
OS   (Colletotrichum gloeosporioides (strain Nara gc5)).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC   Colletotrichum gloeosporioides species complex.
OX   NCBI_TaxID=1213859 {ECO:0000313|EMBL:ELA24666.1};
RN   [1] {ECO:0000313|EMBL:ELA24666.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Nara gc5 {ECO:0000313|EMBL:ELA24666.1};
RA   Gan P.H.P., Ikeda K., Irieda H., Narusaka M., O'Connell R.J., Narusaka Y.,
RA   Takano Y., Kubo Y., Shirasu K.;
RT   "Genome analysis of Colletotrichum orbiculare and Colletotrichum
RT   fructicola.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   EMBL; KB021247; ELA24666.1; -; Genomic_DNA.
DR   RefSeq; XP_007286265.1; XM_007286203.1.
DR   AlphaFoldDB; L2FF32; -.
DR   STRING; 1213859.L2FF32; -.
DR   EnsemblFungi; ELA24666; ELA24666; CGGC5_2056.
DR   HOGENOM; CLU_002633_1_1_1; -.
DR   OrthoDB; 276824at2759; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 3.
DR   Gene3D; 4.10.80.160; -; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   InterPro; IPR039762; Nmd2/UPF2.
DR   InterPro; IPR007193; Upf2/Nmd2_C.
DR   PANTHER; PTHR12839; NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2; 1.
DR   PANTHER; PTHR12839:SF7; REGULATOR OF NONSENSE TRANSCRIPTS 2; 1.
DR   Pfam; PF02854; MIF4G; 2.
DR   Pfam; PF04050; Upf2; 1.
DR   SMART; SM00543; MIF4G; 2.
DR   SUPFAM; SSF48371; ARM repeat; 2.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   DOMAIN          468..658
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   DOMAIN          673..880
FT                   /note="MIF4G"
FT                   /evidence="ECO:0000259|SMART:SM00543"
FT   REGION          246..281
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          419..457
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          908..1160
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        419..443
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        918..950
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        951..970
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1014..1049
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1050..1104
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1114..1128
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1129..1160
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1160 AA;  130662 MW;  A66D814F50194E61 CRC64;
     MDRARKRKLR SLNTRAWEGE TDLFAASKSL DSSLKKNTAF IKRLRTAISA ATLNTFLQEI
     RTLSLHKYLS EIVSACYEGL CKLKSPGEIE AGVEIVSALH QRFGPSEFTE YLGWLLGKGM
     ATPDKSLLKS LAPEVREKEE KERLTRQRVL LRVVTELWLV DVLRTLDDVT RPDDATKGAT
     GKVPELKIKA QSNKTGAAEP FPLEVLKDLL GHDREHVNLP LLVIFVKAFS WDILGVKSAV
     GEGRKTVEED GATKVSNGPA QSDGDTEDST TETDEQPITP PDLQEKFKTI LKKYFEDVKN
     HVVRDQKSIH SQARRNAEAY VKSGEVFEDR QANFEKQVKA QERLVANAQA IADAIGADMP
     DLKDNDDSLG ASNGSIGLVK AGEYLRGLGD GAGIWEDEDE RRFYENLVDL KGKVPGILLD
     DGKKKKPDSE EQVGKKIDPA EASEAPKVPD PSDDQSTAIA NKTIGAQVDA VLARLPDLTN
     KDIIDQAAID FCYLNSKASR NRLIKALTEV PKGRGDLLPS WARLAATLGR YMPDIPKGLV
     DYLDAEFRSL QRRKDKDFLG QVRLSNIRYL AELTKFGIVP EHVVFHCLKV SLDDFSRMNI
     EIICNLLENC GRYLLRNPET SPRMATFLET LQRKKSVQHI GQAERMLIEN AVYYVDPPDR
     PAIQQKERNP MELFIRKLVY MDMTKRNYSK ILKQIRRLHW EEAEVVSILE KVFSKPGKVK
     YGNIHLLAIL LSALYRYHPA FVVRVIDNVM ESISFGLEQN DFKFYQRRIS EVKYIGELYN
     YRMVEHPVIF DTMYKIMTFG HGGPPIPGRL NPFDLPDDFF RIRLIATVLE TCGMYFAKGA
     AGKKLDYFLS FFQYYIYTKH PLPMDIEFII QDTFALTRPQ WKLASNLEEA SKAFQLAIAQ
     DQKVSGADKI IDPDDASIGS SSDDEDGDAD LPEAEADEEE TDSEDEGIED QEIDLSHRDS
     ESEDEAIVVT RQQEQIDPEA EAEFDLPLPV RGKNKEASAG GETGEAPAPV PSSTMAFSLL
     TKKGNRQQTR TVELPSDSTF AVAMKNQQQA EREEQQRIKN LVLNYDLREN DDQDGHDKPT
     SYHHNRSDRG KDRGGQRVRK LQLSDVDWYE SSAKRGNSFA QTHSSCSNAV TERDEKEQSK
     ASLTHHLHSV VDKRGKPAMG
//