ID   L2FX66_COLFN            Unreviewed;       922 AA.
AC   L2FX66;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Guanyl-nucleotide exchange factor {ECO:0000313|EMBL:ELA30907.1};
GN   ORFNames=CGGC5_971 {ECO:0000313|EMBL:ELA30907.1};
OS   Colletotrichum fructicola (strain Nara gc5) (Anthracnose fungus)
OS   (Colletotrichum gloeosporioides (strain Nara gc5)).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC   Colletotrichum gloeosporioides species complex.
OX   NCBI_TaxID=1213859 {ECO:0000313|EMBL:ELA30907.1};
RN   [1] {ECO:0000313|EMBL:ELA30907.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Nara gc5 {ECO:0000313|EMBL:ELA30907.1};
RA   Gan P.H.P., Ikeda K., Irieda H., Narusaka M., O'Connell R.J., Narusaka Y.,
RA   Takano Y., Kubo Y., Shirasu K.;
RT   "Genome analysis of Colletotrichum orbiculare and Colletotrichum
RT   fructicola.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KB020781; ELA30907.1; -; Genomic_DNA.
DR   RefSeq; XP_007280064.1; XM_007280002.1.
DR   AlphaFoldDB; L2FX66; -.
DR   STRING; 1213859.L2FX66; -.
DR   EnsemblFungi; ELA30907; ELA30907; CGGC5_971.
DR   HOGENOM; CLU_008289_0_0_1; -.
DR   OrthoDB; 4248238at2759; -.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR023394; Sec7_C_sf.
DR   InterPro; IPR000904; Sec7_dom.
DR   InterPro; IPR035999; Sec7_dom_sf.
DR   PANTHER; PTHR10663:SF402; ARF GUANINE NUCLEOTIDE EXCHANGE FACTOR SYT1; 1.
DR   PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR   Pfam; PF01369; Sec7; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00222; Sec7; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF48425; Sec7 domain; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50190; SEC7; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN          40..239
FT                   /note="SEC7"
FT                   /evidence="ECO:0000259|PROSITE:PS50190"
FT   DOMAIN          355..485
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          44..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          631..858
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          889..922
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          548..575
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        693..715
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        728..752
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        754..778
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        815..842
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        897..922
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   922 AA;  103275 MW;  14E39740778D347F CRC64;
     MSSLGRDSLE GHLDPGASRT STSIGRKSFG DLFGLNRLRQ NSDLGQRAGT LTPATPGSNT
     SKNNSLQIAR EPIALPEKLE DETPAKYLAR IEEILSRGVI ASALSKGSDP FAAAVLRSYM
     RRFSFFGDPM DMAIRKLLME AELPKETQQI DRCLQAFANR YHECNPGIYA SPDQAYFVAF
     SLLILHTDVF NKNNKHKMQQ PDYLKNTQGE GVSDPILRCF YDNITYTPFI HVEDDVDLNG
     DRLIANRAKR KTLFPGGTPE AAAKRSNREP LDPYTLIIDG KLDILRPSLK DVMELEDHYD
     YLGTAKDLNV KELQRTFFRT GVLQIVSARS RPDAFRDEKS AINPAEAAQG VVDIKITKVG
     LLWRKDVKKK KTRSPWQEWG AILTGAQLYF FRNTTWIKNL MHQYESHVKQ GFYGEPITFK
     PPLPEFKPDG YLPTKEAVAL VDSTYKKHKN AFKYSRPGAF VEEVLLADNE EEMNDWLAKL
     NYAAAFTTSG VRMRGVVGGN YEGQSRRGIR RLGSSASAQV IQTPTGEVSI VRGKIDHQEA
     ESIQAQRRQT MMDAVAKADE EIAIKEQELE IHLRNARHLQ ILSPIQAKTR DQVLSAAAHM
     DVKIKWIRMD MWKSRCHRDV LLKDMSEEQR LQGLVPTKSQ NGHEIREASP SRERPPMLEA
     GSVTSVGRRR RRSSAAISVV QGPAKMAQGE PESPTNDAYQ TPPTSATFNP HKHQNSWDSK
     VSKSQEPVYR KRPCSSSSQS SGDPTFYSPQ QHPTPRRGKD EETSVAEEHH DDVDANERVL
     LEQAGLLGSE SHGNPPERKR TGSLSEAGDA SESRDTPGSI DKQDRTKIRR SLQRTLRESA
     GHLSHHRSRK GKEVITGSAL EDAGREDVLT RGTGSFVVHG KKASVINFGS ELQQLTPEER
     LRQRKPGQRD EPASPARVPR HA
//