ID L2GMN0_VITCO Unreviewed; 356 AA.
AC L2GMN0;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Cation-transporting ATPase {ECO:0000256|RuleBase:RU362082};
DE EC=7.2.2.- {ECO:0000256|RuleBase:RU362082};
GN ORFNames=VICG_01426 {ECO:0000313|EMBL:ELA41562.1};
OS Vittaforma corneae (strain ATCC 50505) (Microsporidian parasite) (Nosema
OS corneum).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Nosematidae;
OC Vittaforma.
OX NCBI_TaxID=993615 {ECO:0000313|EMBL:ELA41562.1, ECO:0000313|Proteomes:UP000011082};
RN [1] {ECO:0000313|Proteomes:UP000011082}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50505 {ECO:0000313|Proteomes:UP000011082};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Didier E., Bowers L., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The genome sequence of Vittaforma corneae strain ATCC 50505.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|RuleBase:RU362082};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362082}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU362082}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type V subfamily. {ECO:0000256|RuleBase:RU362082}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362082}.
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DR EMBL; JH370142; ELA41562.1; -; Genomic_DNA.
DR RefSeq; XP_007604872.1; XM_007604810.1.
DR AlphaFoldDB; L2GMN0; -.
DR STRING; 993615.L2GMN0; -.
DR GeneID; 19882137; -.
DR VEuPathDB; MicrosporidiaDB:VICG_01426; -.
DR HOGENOM; CLU_778906_0_0_1; -.
DR InParanoid; L2GMN0; -.
DR OrthoDB; 5480493at2759; -.
DR Proteomes; UP000011082; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140358; F:P-type transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR006544; P-type_TPase_V.
DR InterPro; IPR047819; P5A-ATPase_N.
DR PANTHER; PTHR45630; CATION-TRANSPORTING ATPASE-RELATED; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF12409; P5-ATPase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362082};
KW Magnesium {ECO:0000256|RuleBase:RU362082};
KW Membrane {ECO:0000256|RuleBase:RU362082};
KW Metal-binding {ECO:0000256|RuleBase:RU362082};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362082};
KW Reference proteome {ECO:0000313|Proteomes:UP000011082};
KW Translocase {ECO:0000256|RuleBase:RU362082};
KW Transmembrane {ECO:0000256|RuleBase:RU362082};
KW Transmembrane helix {ECO:0000256|RuleBase:RU362082}.
FT TRANSMEM 192..209
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362082"
FT DOMAIN 26..82
FT /note="P5B-type ATPase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12409"
SQ SEQUENCE 356 AA; 40518 MW; 190269D44734B31F CRC64;
MVSTLQQSIN FVARTHISDL KNAFYNLLTF GMFYVVCRLS KRMEIILKTS PAILSEANCV
LLEDQYGQYQ IVMVKRIPTR NTLVLSRYIK DHCCTILDTC YGRFIYDYKL DKFVIPSYIF
NVKKSFDDVY QSYIMKSKEE ERTENYEKTI IFGKNELGMQ IPELSEIFLN QLFDPLVLWE
IISLIIWISI NYIIYASVAS IIFTAMFVIE INREIKNRNA LLRSLRVSNV RALREGAFRS
VPECDILPGD IVYIDTTDNF TCDVEILKGD VITDESFLTG EAVPICKGIG SIVYSGTKVI
KSTSSSVSLN NTKLEKLVRV KNLTRSKASS FVAPVSSFDQ TDNSAIGIVL KTGKKN
//
