ID L2GT72_VAVCU Unreviewed; 389 AA.
AC L2GT72;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=26S proteasome subunit P45 family protein {ECO:0000313|EMBL:ELA46824.1};
GN ORFNames=VCUG_01668 {ECO:0000313|EMBL:ELA46824.1};
OS Vavraia culicis (isolate floridensis) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Pleistophoridae;
OC Vavraia.
OX NCBI_TaxID=948595 {ECO:0000313|EMBL:ELA46824.1, ECO:0000313|Proteomes:UP000011081};
RN [1] {ECO:0000313|Proteomes:UP000011081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=floridensis {ECO:0000313|Proteomes:UP000011081};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Becnel J., Sanscrainte N., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The genome sequence of Vavraia culicis strain floridensis.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AAA ATPase family.
CC {ECO:0000256|ARBA:ARBA00006914, ECO:0000256|RuleBase:RU003651}.
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DR EMBL; GL877431; ELA46824.1; -; Genomic_DNA.
DR RefSeq; XP_008074685.1; XM_008076494.1.
DR AlphaFoldDB; L2GT72; -.
DR STRING; 948595.L2GT72; -.
DR GeneID; 19879542; -.
DR VEuPathDB; MicrosporidiaDB:VCUG_01668; -.
DR HOGENOM; CLU_000688_2_0_1; -.
DR InParanoid; L2GT72; -.
DR OMA; TANCRVA; -.
DR OrthoDB; 1465143at2759; -.
DR Proteomes; UP000011081; Unassembled WGS sequence.
DR GO; GO:0008540; C:proteasome regulatory particle, base subcomplex; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd19502; RecA-like_PAN_like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032501; Prot_ATP_ID_OB_2nd.
DR PANTHER; PTHR23073; 26S PROTEASOME REGULATORY SUBUNIT; 1.
DR PANTHER; PTHR23073:SF155; 26S PROTEASOME REGULATORY SUBUNIT 10B; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF16450; Prot_ATP_ID_OB_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU003651};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU003651};
KW Proteasome {ECO:0000256|ARBA:ARBA00022942, ECO:0000313|EMBL:ELA46824.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000011081}.
FT DOMAIN 166..304
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT COILED 9..46
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 389 AA; 44221 MW; 0CCC5EAC38BD16ED CRC64;
MSFTTAYFMN ETQRLHNEIE NKRMELKKLN KKQYDLNNQV RMLKEEIRIV QEPSANVGTV
IKKMGKNKVL VKTQPDGKYM VDVDEKINME ELKLNTRVAL RSDNYKLIRT LPTIVDPIVS
LMMVEKVPDA TYDMIGGLKQ QIKEIREVIE LPIKNPELFE NLGITQPKGV LLYGPPGTGK
TLLARAVAHH TDCKFIRVSG TELVQKYIGE GSRLVRELFV MAREHAPSII FMDEIDSIGS
TRSEGGKGDS EVQRTMLELL NQLDGFENRS DIKVIMATNR IDILDPALLR TGRIDRKIEF
PNPNEEARLE ILKIHSRKMN LVRGIRLSEI THKLVNASGA EVKGVCTEAG MFALREMRVH
VTQEDFELAV AKVMKKADDP ASDLRKLLK
//
