ID L2GV44_VAVCU Unreviewed; 380 AA.
AC L2GV44;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=choline-phosphate cytidylyltransferase {ECO:0000256|ARBA:ARBA00026101};
DE EC=2.7.7.15 {ECO:0000256|ARBA:ARBA00026101};
GN ORFNames=VCUG_01233 {ECO:0000313|EMBL:ELA47237.1};
OS Vavraia culicis (isolate floridensis) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Pleistophoridae;
OC Vavraia.
OX NCBI_TaxID=948595 {ECO:0000313|EMBL:ELA47237.1, ECO:0000313|Proteomes:UP000011081};
RN [1] {ECO:0000313|Proteomes:UP000011081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=floridensis {ECO:0000313|Proteomes:UP000011081};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Becnel J., Sanscrainte N., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The genome sequence of Vavraia culicis strain floridensis.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cytidylyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010101}.
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DR EMBL; GL877421; ELA47237.1; -; Genomic_DNA.
DR RefSeq; XP_008074253.1; XM_008076062.1.
DR AlphaFoldDB; L2GV44; -.
DR STRING; 948595.L2GV44; -.
DR GeneID; 19879113; -.
DR VEuPathDB; MicrosporidiaDB:VCUG_01233; -.
DR HOGENOM; CLU_034585_1_2_1; -.
DR InParanoid; L2GV44; -.
DR OMA; HCKYVDE; -.
DR OrthoDB; 5474784at2759; -.
DR Proteomes; UP000011081; Unassembled WGS sequence.
DR GO; GO:0004105; F:choline-phosphate cytidylyltransferase activity; IEA:InterPro.
DR CDD; cd02174; CCT; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR041723; CCT.
DR InterPro; IPR004821; Cyt_trans-like.
DR InterPro; IPR045049; Pcy1-like.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR NCBIfam; TIGR00125; cyt_tran_rel; 1.
DR PANTHER; PTHR10739:SF13; CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR10739; CYTIDYLYLTRANSFERASE; 1.
DR Pfam; PF01467; CTP_transf_like; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Phospholipid biosynthesis {ECO:0000256|ARBA:ARBA00023209};
KW Phospholipid metabolism {ECO:0000256|ARBA:ARBA00023264};
KW Reference proteome {ECO:0000313|Proteomes:UP000011081}.
FT DOMAIN 148..275
FT /note="Cytidyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF01467"
SQ SEQUENCE 380 AA; 43805 MW; 0AAA04A2F9A06EC3 CRC64;
MKSLNMERTK NCKVRAKSAI DGTMSVCDRE RSAINAHKNG SNDAINAHKN GSNDAINAHK
NGSNDAINAH KNGMNIKTID ERVAHPKTIN DTCSATAQKT GNTEDAAPPN DDMILAKPFY
FNSSQFVFED QIEEKYYPIP KNRPVRIYCD GVYDLFHYGH MRSLMQAKHL FPNVHLLVGV
TNDCITLQNK GSLVFNEHER TESVRHCRYV DEVIENAPWS ITGTFLETHR IDYVCHDNVP
YSCAHSADVY DSLKRSNKFI PTRRTFGIST TNIITKIVKD YDLFVRRQLE KGINADELNL
SFFTKESINV KNTIKNIEAD LKNEIKEIRE ELRIALLYWE RVSNEMISTF SHRFARTVNE
HSLFKKIFRK IILMIERKRR
//
