ID L2GWA7_VAVCU Unreviewed; 808 AA.
AC L2GWA7;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 28-JUN-2023, entry version 36.
DE SubName: Full=VacB and RNase II family 3'-5' exoribonuclease {ECO:0000313|EMBL:ELA47365.1};
GN ORFNames=VCUG_01134 {ECO:0000313|EMBL:ELA47365.1};
OS Vavraia culicis (isolate floridensis) (Microsporidian parasite).
OC Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Pleistophoridae;
OC Vavraia.
OX NCBI_TaxID=948595 {ECO:0000313|EMBL:ELA47365.1, ECO:0000313|Proteomes:UP000011081};
RN [1] {ECO:0000313|Proteomes:UP000011081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=floridensis {ECO:0000313|Proteomes:UP000011081};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Becnel J., Sanscrainte N., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The genome sequence of Vavraia culicis strain floridensis.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the RNR ribonuclease family.
CC {ECO:0000256|RuleBase:RU003901}.
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DR EMBL; GL877419; ELA47365.1; -; Genomic_DNA.
DR RefSeq; XP_008074156.1; XM_008075965.1.
DR AlphaFoldDB; L2GWA7; -.
DR STRING; 948595.L2GWA7; -.
DR GeneID; 19879015; -.
DR VEuPathDB; MicrosporidiaDB:VCUG_01134; -.
DR HOGENOM; CLU_002333_5_0_1; -.
DR InParanoid; L2GWA7; -.
DR OMA; NCEETRD; -.
DR OrthoDB; 945235at2759; -.
DR Proteomes; UP000011081; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR Gene3D; 2.40.50.690; -; 1.
DR Gene3D; 2.40.50.700; -; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR041505; Dis3_CSD2.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR001900; RNase_II/R.
DR InterPro; IPR022966; RNase_II/R_CS.
DR PANTHER; PTHR23355:SF9; DIS3-LIKE EXONUCLEASE 2; 1.
DR PANTHER; PTHR23355; RIBONUCLEASE; 1.
DR Pfam; PF17849; OB_Dis3; 1.
DR Pfam; PF00773; RNB; 1.
DR SMART; SM00955; RNB; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 2.
DR PROSITE; PS01175; RIBONUCLEASE_II; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000011081}.
FT DOMAIN 408..700
FT /note="Ribonuclease II/R"
FT /evidence="ECO:0000259|SMART:SM00955"
SQ SEQUENCE 808 AA; 93760 MW; E15333A9EAD52B61 CRC64;
MIACEQTYAF NRRRKLIKRV VECYKRVNIP CGFACCTSTT KLVKDKYYIA EADILIKFKS
LLFSENVIVL QSVLKEIKLK NIRRYNSYTR IIKRNGIFVF YDDFRLEEMN KEEERRMLVR
DGNMTIYEQK WPSKTRRALL FYHSHVPGVE INILDVENCS EFMNDPLLCD YVTVPDTPDD
DSYREYTNEG SVGFFHSSYY NYFSGTIYCE NKKYYVNNRL DVNRALNGDE VYFKIVESDE
VQAEVLETDT DAMSASGSDK VDTKNERKEF AYITGIKERK DRIIVGTILN STISGTGTQN
VLIKPMDKKY PPCRIQTSNV GRIKDKRLKF IISEWKETSK YPNAVYLGTI GPIKDVEVEI
NSILLLNEIP NAPLSKNYHE ETERFGHEQT NCEETRDLQR FAEINSNRLD LRDEYVFSID
PPGCTDIDDA LHCKMGDTIE IGVHIADVSS YVLRNTTIDE EAKRRGTTVY LNDRRIDMLP
DVLSSDLCSL RSNVDRLALS VIFQFDSNFN IINTKVSETI IQSKESFTYE EAQRILNDTN
HRSYASLHRL YEVSRKLKQS RIDSGALILN IGETLVREES DKLRINTKCE AETCSIVEEF
MILANVTIAK FMYEHIRNCS LLRRHPETEI KEIESEIESV RSMLKRRSMA QATYFSSGTV
PFADFRHFGL AEPIYTHFTS PIRRYADLVV HRLVKSIMFQ SDYGYDDYSI DALTKHLNAR
HRGAQIASRE CNFLFLYLYL SEHEPVTQAY VIKSLANGSM VYIPEYDIDG FITSVRAVSE
EVKVKIVKND ENFYVNRWIT LEEMNEGV
//
