ID L5JMQ6_PTEAL Unreviewed; 550 AA.
AC L5JMQ6;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Triadin {ECO:0000256|ARBA:ARBA00016711};
GN ORFNames=PAL_GLEAN10018672 {ECO:0000313|EMBL:ELK00699.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK00699.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}. Sarcoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004157}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004157}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB031156; ELK00699.1; -; Genomic_DNA.
DR AlphaFoldDB; L5JMQ6; -.
DR STRING; 9402.L5JMQ6; -.
DR InParanoid; L5JMQ6; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR InterPro; IPR007943; Asp-B-hydro/Triadin_dom.
DR InterPro; IPR019372; LHFPL.
DR InterPro; IPR010798; Triadin.
DR PANTHER; PTHR14106; TRIADIN; 1.
DR PANTHER; PTHR14106:SF0; TRIADIN; 1.
DR Pfam; PF05279; Asp-B-Hydro_N; 1.
DR Pfam; PF10242; L_HMGIC_fpl; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 78..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 246..276
FT /note="Aspartyl beta-hydroxylase/Triadin"
FT /evidence="ECO:0000259|Pfam:PF05279"
FT REGION 317..504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 523..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 329..407
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..429
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 430..445
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 459..500
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 550 AA; 62166 MW; 95CBF049281BACF6 CRC64;
MKKHLTLCLP LPLRSLSTIF PMSGNTLLDR RWRGHLQAGY FRLFSYCISN GYSRELTCRN
IFTDFSTLPL GTFKDASFFI SLSMMLIIAC IICFTLFFFY NRFPSKHPVT KILLNYLKLI
LLPEPQVLLW KGLRLLPGGE LCREETKFNK TTKKQQKQPG KRRALTFSHR ILHQSSPILK
YSAKYHLTGT FACLFLSPTT MTEITAEGNA STTTTVIDNK NGSVPKSPGK ILKRTVTEDI
VTTFSSPAAW LLVIALIITW SAVAVVMFDL VDYKNFSASS ISKIGSDPIK FVHHAVEETT
DWVYGFFSLL SDIISSDEED DDDGDEDTDK VTQREKEKDK IKEKEKPEKK EEKKAKTKEK
TEEKTKKEVK SGKQEKVKQM TAKVKEVQKT SSKPKEKDEK ETAAVSKHEQ KAATPQGTIT
RQQLNAIHHR SQRVMKERNE QQPGKAPETK QETIKVAAQA AAKKDEKKED PQVKKEKPEE
KFEDVPASKK AKEAEDVSST KKQKSPISFF QCVYLDGYNG YGFQFPVTPA QRPGEGSSPP
GSPGQKQQGQ
//
