ID L5JRP3_PTEAL Unreviewed; 245 AA.
AC L5JRP3;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Interleukin-1 receptor accessory protein {ECO:0000313|EMBL:ELK00808.1};
GN ORFNames=PAL_GLEAN10018245 {ECO:0000313|EMBL:ELK00808.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK00808.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
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DR EMBL; KB031155; ELK00808.1; -; Genomic_DNA.
DR AlphaFoldDB; L5JRP3; -.
DR STRING; 9402.L5JRP3; -.
DR eggNOG; ENOG502QRDG; Eukaryota.
DR InParanoid; L5JRP3; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR015621; IL-1_rcpt_fam.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11890:SF20; INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN; 1.
DR PANTHER; PTHR11890; INTERLEUKIN-1 RECEPTOR FAMILY MEMBER; 1.
DR Pfam; PF01582; TIR; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Receptor {ECO:0000313|EMBL:ELK00808.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 1..81
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 103..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 223..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 245 AA; 27010 MW; D4929C754F2FB847 CRC64;
MIVVLSPDYV TEKSISMLEF KLGVMCQNSI ATKLIVVEYR PLEHPHPGIL QLKESVSFVS
WKGEKSKHSG SKFWKALRLA LPLRSLSASS GWNESCSSQS DISLDHVQRR RSRLKEPPEL
QSSGRAAGAS PAPGTMSKHR GKPSATCRCC VTYCEGESHL RSKSRAEIHT QPQWETHLSF
PEVQLRLDDL PASVMPAYIP CAVNRRKKCG CTNNLRLKKK IKEGPSAASA HKAATCPNPL
AQGPQ
//
