ID L5JX31_PTEAL Unreviewed; 307 AA.
AC L5JX31;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=GDNF family receptor alpha-3 {ECO:0000313|EMBL:ELK03051.1};
GN ORFNames=PAL_GLEAN10016823 {ECO:0000313|EMBL:ELK03051.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK03051.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SIMILARITY: Belongs to the GDNFR family.
CC {ECO:0000256|ARBA:ARBA00005961}.
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DR EMBL; KB031114; ELK03051.1; -; Genomic_DNA.
DR AlphaFoldDB; L5JX31; -.
DR STRING; 9402.L5JX31; -.
DR eggNOG; ENOG502QWSW; Eukaryota.
DR InParanoid; L5JX31; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR Gene3D; 1.10.220.110; GDNF binding domain; 1.
DR InterPro; IPR016017; GDNF/GAS1.
DR InterPro; IPR037193; GDNF_alpha.
DR InterPro; IPR003438; GDNF_rcpt.
DR InterPro; IPR003505; GDNF_rcpt_A3.
DR PANTHER; PTHR10269:SF15; GDNF FAMILY RECEPTOR ALPHA-3; 1.
DR PANTHER; PTHR10269; GDNF RECEPTOR ALPHA; 1.
DR Pfam; PF02351; GDNF; 2.
DR PRINTS; PR01319; GDNFRALPHA3.
DR PRINTS; PR01316; GDNFRECEPTOR.
DR SMART; SM00907; GDNF; 2.
DR SUPFAM; SSF110035; GDNF receptor-like; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:ELK03051.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 56..133
FT /note="GDNF/GAS1"
FT /evidence="ECO:0000259|SMART:SM00907"
FT DOMAIN 142..234
FT /note="GDNF/GAS1"
FT /evidence="ECO:0000259|SMART:SM00907"
SQ SEQUENCE 307 AA; 34351 MW; 7BC2DC7E69EE527A CRC64;
MKNQTACLDI YWTIHPARSL GDYELDVSPY EDTVTRKPWK MNLSKLNMLK PDSDLCLKFA
MLCTLNDKCD RLRKAYGEAC SGPRCQHHTC LRQLRAFFEK ASEPHAQGLL LCPCAPGDLG
CGKRRRNTIA PSCSLPSGTS NCLELRRLCL SNPLCRSRLA DFQTHCHPMD ILGTCTTEKS
RCLRAYMGLI GTTMTPNFVS NINASVALSC TCRGSGNLQE ECERLEESFS HNPCLTEAIA
SKMLLHSQLF SQDWTDSTLA IMERQLDSLE ALFSLYYTQP DLLPTRGIGH HRLAISSGDK
QLYLALS
//
