ID   L5JYE5_PTEAL            Unreviewed;       275 AA.
AC   L5JYE5;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=GRAM domain-containing protein 2 {ECO:0000313|EMBL:ELK03526.1};
DE   Flags: Fragment;
GN   ORFNames=PAL_GLEAN10013575 {ECO:0000313|EMBL:ELK03526.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC   Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK03526.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
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DR   EMBL; KB031080; ELK03526.1; -; Genomic_DNA.
DR   AlphaFoldDB; L5JYE5; -.
DR   STRING; 9402.L5JYE5; -.
DR   InParanoid; L5JYE5; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR004182; GRAM.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR042624; RAMD2A.
DR   PANTHER; PTHR46973; GRAM DOMAIN-CONTAINING PROTEIN 2A; 1.
DR   PANTHER; PTHR46973:SF1; GRAM DOMAIN-CONTAINING PROTEIN 2A; 1.
DR   Pfam; PF02893; GRAM; 1.
DR   SMART; SM00568; GRAM; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        233..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          49..116
FT                   /note="GRAM"
FT                   /evidence="ECO:0000259|SMART:SM00568"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ELK03526.1"
SQ   SEQUENCE   275 AA;  31648 MW;  C58ED123251D3313 CRC64;
     NQQMHGKTAS LKSPVSRTEK LDRVQAPPDS RTSQPQPVCL QTLLSKYNQQ YHKLFKDIPL
     EEVVLKVCSC ALQRDLLLQG RLYISPNWLC FHASLFGKDI KVVIPLLSVQ MIKKHKMARL
     FPNGLAITTN TSQKYVFVSL LSRDSVYDTL RRVCTHLQEV LIPEMKWRKV CPASRTPFLQ
     DNIPSIPRVS VDSMDSFLPS RKPPGSENAV CEEEMLEEVP RSNQELQLWD YRLLKVFFVL
     ICFLIMSSSY LAFRISQLEQ QLCSLNWDSP VPGHR
//