ID   L5JZ99_PTEAL            Unreviewed;      1396 AA.
AC   L5JZ99;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=Tetratricopeptide repeat protein 21B {ECO:0000313|EMBL:ELK04660.1};
GN   ORFNames=PAL_GLEAN10025920 {ECO:0000313|EMBL:ELK04660.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC   Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK04660.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
CC   -!- SIMILARITY: Belongs to the TTC21 family.
CC       {ECO:0000256|ARBA:ARBA00010935}.
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DR   EMBL; KB031068; ELK04660.1; -; Genomic_DNA.
DR   STRING; 9402.L5JZ99; -.
DR   eggNOG; ENOG502QQAB; Eukaryota.
DR   InParanoid; L5JZ99; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 5.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR040364; TTC21A/TTC21B.
DR   PANTHER; PTHR14699; STI2 PROTEIN-RELATED; 1.
DR   PANTHER; PTHR14699:SF1; TETRATRICOPEPTIDE REPEAT PROTEIN 21B; 1.
DR   Pfam; PF14559; TPR_19; 1.
DR   Pfam; PF13181; TPR_8; 3.
DR   SMART; SM00028; TPR; 17.
DR   SUPFAM; SSF81901; HCP-like; 1.
DR   SUPFAM; SSF48452; TPR-like; 4.
DR   PROSITE; PS50005; TPR; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT   REPEAT          802..835
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          1032..1065
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   1396 AA;  159342 MW;  56E6D1B4C49AE0C8 CRC64;
     MDSQGLKVSG WNLDVGCFGG WRGFGGRGDS TGRLREGVII PLLCSLGTPA SQGGPVAYIT
     WSSCVDTAWN LEVRGSHSLA LLSELPLTLI NYYCQERYFH HVLLVASEGI KRYSNDPVFR
     FYHAYGTLME GKIQEALREF EAIKNKQDIS LCSLIALIYA HKMSPNPDRE AILESDAKVK
     EQRKGAGPKA LYHAGLFLWH VGRHDKAREY IDRMIKMSNG SKEGQVLRAW LDITRGKEPY
     TKKALRYFEE GLQNGNDIFA LLGKAQCLEM RQNYSGALET VNQIIVNFPS FLPAFVQKMK
     LQLALQDWDQ TIEIAQRLML QDKQNVEALR MLALYYLCRE GDIEKAATTL ENLGDALDAM
     EPQNAPLFYK ITIAFSRTCG RNQLILQKIQ TFLERAFSLN PQQSEYAAEF GYQMILQGKV
     KEASKWYKTA MALDETSVSA LIGFIRCQLI EGQLQDADQQ LEFLSEIQQS IGKSAELTFL
     HALLAMKKNK RQEEVINLLN DVLDTHFSHL EDLPLGIQYF EKLNPDFLLE IITEYLNFCP
     MQPASPGQPL SPLLRRCTSI LETIVRTVPG LLQAVFLIAK VKYLSGDIEA AYNNLQHCLE
     HSPSYADAHL LMAQVYLSQE NFKLCSQSLE LCLSYNFKVR EYPLYHLIKA QSQKKMGEIA
     EAIKTLHMAM SLPGMRNIGA SSKSKYKKTE VDASHRLSIF LELVEVHRLN GEQHEAAKVL
     QDAIHEFSGT SEELRVTIAN ADLALAQGDV ERALSMLRNV TSEQPYFIEA KEKMADIYLK
     HRKEKMLYIT CYREIAERMP SPRSFLLLGD AYMNIQEPEE AIVAYEQALN QNPKDGTLAS
     KIGKALVKTH NYSKAITYYE AAMKSGQQNY LCYDLAELLL KLKWYDKAEK VLQHALAHEP
     VNELSALMED GRSQVLLAKV YSKMERLGDA VTSLQQAREL QARVLKRVQI EQPDAVPAQK
     HLAAEICAEI AKHSVAQRDY EKAIKFYREA LVHCETDNKI MLELARLYLA QDDPDACLRH
     CALLLQSDQD NEAATMMMAD LMFRKQDYEQ AVFHLQQLLE RKPDNYMTLS RLIDFLRRCG
     KLEDVPRFFL MAEKCNSRAK LEPGYQYCKG LYLWYTGEPN DALRHFNKAR KDSDWGQNSL
     YNMIEICLNP DNETVGGEVF ENLDGDLGNS TEKQESVQLA VRTAEKLLKE LKPQTVQGHV
     QLRVMENYCL MATKQKSNVE QALNTFTEIA TSEKDHIPAL LGMATAYMIL KQTPRARNQL
     KRIAKMNWNP IDAEDFERSW LLLADIYIQS AKYDMAEELL KRCLRHNRSC CKAYEYMGYI
     MEKEQAYTDA ALNYEMAWKH GNQTNPSVGY KLAFNYLKAK RYVDAIDVCH QVLEAHPTYP
     KIRKDILDKA RTSLRP
//