ID L5JZS9_PTEAL Unreviewed; 250 AA.
AC L5JZS9;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Rho GTPase-activating protein 15 {ECO:0000313|EMBL:ELK04592.1};
GN ORFNames=PAL_GLEAN10025838 {ECO:0000313|EMBL:ELK04592.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK04592.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
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DR EMBL; KB031068; ELK04592.1; -; Genomic_DNA.
DR AlphaFoldDB; L5JZS9; -.
DR STRING; 9402.L5JZS9; -.
DR InParanoid; L5JZS9; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR23176:SF108; RHO GTPASE-ACTIVATING PROTEIN 15; 1.
DR PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 65..245
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
SQ SEQUENCE 250 AA; 28497 MW; 16E829A55D0E0F5A CRC64;
MTSRTTVRSE PQKLGERLTI TTVSGNEFLL QSDIDFIILD WFHAIKNAID RLITTVSGNE
FLLQSDIDFI ILDWFHAIKN AIDRLPKNPS SLPRNLELFK IQRSSSTELL SHYDSDIKEQ
KPEHRKSLSL DVDGIYRVSG NLATIQKLRF IVNQEKQDNN TRIETVKSLV QKLPPPNRDT
MKVLFGHLTK IVAKASKNLM STQSLGIVFG PTLLRAEHET GNMAIHMVYQ NQIAELMLSE
YSKIFGSEED
//
