ID L5K1Z0_PTEAL Unreviewed; 345 AA.
AC L5K1Z0;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Interleukin-10 receptor beta chain {ECO:0000313|EMBL:ELK04503.1};
GN ORFNames=PAL_GLEAN10025737 {ECO:0000313|EMBL:ELK04503.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK04503.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; KB031068; ELK04503.1; -; Genomic_DNA.
DR AlphaFoldDB; L5K1Z0; -.
DR STRING; 9402.L5K1Z0; -.
DR eggNOG; ENOG502S2QA; Eukaryota.
DR InParanoid; L5K1Z0; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015373; Interferon/interleukin_rcp_dom.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR PANTHER; PTHR20859:SF50; INTERLEUKIN-10 RECEPTOR SUBUNIT BETA; 1.
DR Pfam; PF09294; Interfer-bind; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR PROSITE; PS50853; FN3; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:ELK04503.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 239..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 41..129
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 132..233
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 322..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 345 AA; 39210 MW; E701EDD2C6C8EAEB CRC64;
MEPAVQETRV LAIVIFVGHF SEEKRCRHFP FIFTALGMVP PPENVRMNSV NFQNILQWES
PAFPKAGLTF TAQYLSYKKF QDMCTSTALT ECDFSSLSKY GDHTLRVRAE LAEEHSDWVN
VTFSPVDDTI IGPPGMQVEA LANSLHIRFL APKIEKEHET WTMKNIYNSW AYNVQYWKNG
SDEKILVTCQ YDFEVLRNLE PWTTYCVQVQ GFLPDRNKTG EWSEPVCEQT VNDETAPSWI
VVAIILTASV CVACLLLLGC FALMWCIYKK TKYAFAHGNK LPQHLKEFLG HPHHSRLLFF
SFPLSDENDV FDKLSVVTEV SESSKQNPGD SCSLRTPAGQ GLLSS
//
