ID L5K233_PTEAL Unreviewed; 402 AA.
AC L5K233;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=E3 ubiquitin-protein ligase Arkadia N-terminal domain-containing protein {ECO:0000259|Pfam:PF15303};
GN ORFNames=PAL_GLEAN10023076 {ECO:0000313|EMBL:ELK05635.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK05635.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KB031041; ELK05635.1; -; Genomic_DNA.
DR AlphaFoldDB; L5K233; -.
DR STRING; 9402.L5K233; -.
DR eggNOG; ENOG502QUC3; Eukaryota.
DR InParanoid; L5K233; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR029306; RNF111_N.
DR PANTHER; PTHR16200; RING ZINC FINGER; 1.
DR PANTHER; PTHR16200:SF5; SIMILAR TO HYPOTHETICAL PROTEIN; 1.
DR Pfam; PF15303; RNF111_N; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 84..223
FT /note="E3 ubiquitin-protein ligase Arkadia N-terminal"
FT /evidence="ECO:0000259|Pfam:PF15303"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 60..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 195..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..182
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 402 AA; 43286 MW; 9485227314E5D238 CRC64;
MEEAVGKVEE LIESEVPPKT SEQETAKEED GSVELEPQVQ KDGVVDSTVL SSMPCLLMEL
RRDSSESQLA STESDKPTTG RVYESDSSNH CMLSPSSSGH LADSDTLSSA EENEPSQAET
AVEGDPSGVS GATVGRKSRR SRSESETSTM AAKKNRQSSD KQNGRVAKVK GHRSQKHKER
IRLLRQKREA AARKKYNLLQ DSSTSDSDLT CDSSTSSSDD DEEVSGSSKT ITAEIPDGPP
VVAHYDMSDT SSDPEVVNVD TLLAAAVVQE HSNSIGGQDT GATWRTSELL EELNAEAGHL
DPGFLASDKT SVGNVPLNEE INIASSDSEV EIVGVQEHAR CVHPRGGVIQ SVSSWKHGSG
TPYVSNRQAQ SWTAVTPQQT WASPAEVVDL TLDEDSRRKY LL
//
