ID   L5K357_PTEAL            Unreviewed;       139 AA.
AC   L5K357;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=Keratin, type I cytoskeletal 19 {ECO:0000256|ARBA:ARBA00040324};
DE   AltName: Full=Cytokeratin-19 {ECO:0000256|ARBA:ARBA00041710};
DE   AltName: Full=Keratin-19 {ECO:0000256|ARBA:ARBA00042489};
GN   ORFNames=PAL_GLEAN10026177 {ECO:0000313|EMBL:ELK04893.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC   Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK04893.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA   Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA   Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA   Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the evolution of
RT   flight and immunity.";
RL   Science 339:456-460(2013).
CC   -!- FUNCTION: Involved in the organization of myofibers. Together with
CC       KRT8, helps to link the contractile apparatus to dystrophin at the
CC       costameres of striated muscle. {ECO:0000256|ARBA:ARBA00037562}.
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DR   EMBL; KB031068; ELK04893.1; -; Genomic_DNA.
DR   AlphaFoldDB; L5K357; -.
DR   STRING; 9402.L5K357; -.
DR   InParanoid; L5K357; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 1.20.5.500; Single helix bin; 1.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR002957; Keratin_I.
DR   PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR   PANTHER; PTHR23239:SF14; KERATIN, TYPE I CYTOSKELETAL 19; 1.
DR   Pfam; PF00038; Filament; 1.
DR   SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Intermediate filament {ECO:0000256|ARBA:ARBA00022754};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT   DOMAIN          90..131
FT                   /note="IF rod"
FT                   /evidence="ECO:0000259|Pfam:PF00038"
FT   REGION          1..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   139 AA;  15465 MW;  1EFECCF7B4A015C8 CRC64;
     MLSYMRRQSE VMAEKNQKDA EAWFTSQTEE MNREQDEGHQ PEAHPPGSGD QAAVSAQGES
     CPGGHAGRNG GLLWSLAGTD PGPNVSTVAQ RSDVRAEIEQ QNLEYQQLMD IKTWLEQEIT
     TYCSLLEGQD TYYNNLPTT
//