ID L5K3X2_PTEAL Unreviewed; 614 AA.
AC L5K3X2;
DT 06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=GTPase IMAP family member 8 {ECO:0000313|EMBL:ELK05188.1};
GN ORFNames=PAL_GLEAN10007567 {ECO:0000313|EMBL:ELK05188.1};
OS Pteropus alecto (Black flying fox).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Chiroptera; Megachiroptera; Pteropodidae;
OC Pteropodinae; Pteropus.
OX NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK05188.1, ECO:0000313|Proteomes:UP000010552};
RN [1] {ECO:0000313|Proteomes:UP000010552}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23258410; DOI=10.1126/science.1230835;
RA Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y., Zhou P.,
RA Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y., Sun X.,
RA Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G., Wang L.F.,
RA Wang J.;
RT "Comparative analysis of bat genomes provides insight into the evolution of
RT flight and immunity.";
RL Science 339:456-460(2013).
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000256|ARBA:ARBA00008535}.
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DR EMBL; KB031043; ELK05188.1; -; Genomic_DNA.
DR AlphaFoldDB; L5K3X2; -.
DR STRING; 9402.L5K3X2; -.
DR eggNOG; ENOG502RB0C; Eukaryota.
DR InParanoid; L5K3X2; -.
DR Proteomes; UP000010552; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd01852; AIG1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903:SF73; GTPASE IMAP FAMILY MEMBER 8; 1.
DR PANTHER; PTHR10903; GTPASE, IMAP FAMILY MEMBER-RELATED; 1.
DR Pfam; PF04548; AIG1; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS51720; G_AIG1; 3.
PE 3: Inferred from homology;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000010552}.
FT DOMAIN 1..166
FT /note="AIG1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51720"
FT DOMAIN 201..390
FT /note="AIG1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51720"
FT DOMAIN 391..586
FT /note="AIG1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51720"
FT REGION 172..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 614 AA; 68618 MW; 080D0B3ECC2B1162 CRC64;
MVTKTCRRES SDTASGKVVV IDTPDIFSSM ASAGDKDHHV QQCRELSAPI LHAFLLVIPL
GYYRAEDRET IEGIQKVFGA EARRHTFVIF TWGHDLGDES IEDYTENRED LRELLANYGN
RYCAFDNKAG EQERLSQARK LLHEVKRMVA ENREPYHVTC GKAGDAFQDC ENKASSQKGD
NPHGPGELPR QAPECPQTRG TSELKVLLVG KRGAGKSAAG NRLLGKQFFE TKFSEQPVTQ
RFQSERRTWR EREILIIDSP NLSLSTDFRS ELQEHASPGP HAFLLVTPLG SFGKEDQEVL
RIMENSFGHK FYEFMIILFT RKEDLGDQEL HTFPETGDTA LRDVLRKCGD RSSAFGYRVT
RAEEQRQVDE LLEKLVSMVQ QSGHRPCAFQ KETLRLVLLG RTGSGKSATG NTILGRSAFA
SLLSARPVTK TCQTEKRTDQ DVVVVDTPGL CPETQEAQLE EIVSCEDMNT ILVLVFQLGR
FTGEDAKVVA MLETIFGEDV LKYTILLFTR KEDLEGGSLE DYLENMKNGA LKKVVKKCGG
RVCAFNNKIT GQAREQQAEA LLKMANELIS SHGGQGYSQG HGIDESVGKL KNMVKSLKEK
ALDTFKVFSV SKTL
//
